Original title: Electrochemically Switchable DNA Tags
Authors: Vidláková, Pavlína ; Havran, Luděk ; Fojta, Miroslav
Document type: Papers
Conference/Event: Moderní elektrochemické metody /37./, Jetřichovice (CZ), 20170515
Year: 2017
Language: eng
Abstract: DNA labelling is used for the improvement of sensitivity and selectivity of its electrochemical detection. Attachment of a new electroactive group into DNA strand can give rise to a new electrochemical signal. For analysis of label DNA is often advantageous to use redox tags giving reversible redox signal because of the possibility of performing several repeated measurements with one sample. Some redox tags give reversible redox signal directly in their introduced forms. Reduction/oxidation of other redox tags is irreversible but reduction/oxidation of these groups can give rise to new groups that yield reversible electrochemistry.
Keywords: dna; enzymatic incorporation; nucleoside triphosphates; Voltammetry
Project no.: GA15-08434S (CEP)
Funding provider: GA ČR
Host item entry: XXXVII. Moderní elektrochemické metody. Sborník přednášek mezinárodní odborné konference, ISBN 978-80-905221-5-2

Institution: Institute of Biophysics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0297863

Permalink: http://www.nusl.cz/ntk/nusl-396398


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Research > Institutes ASCR > Institute of Biophysics
Conference materials > Papers