Original title: Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode
Authors: Hejduková, M. ; Špaček, Jan ; Fojta, Miroslav ; Havran, L. ; Renciuk, D.
Document type: Papers
Conference/Event: Moderní elektrochemické metody /38./, Jetřichovice (CZ), 20180521
Year: 2018
Language: eng
Abstract: Electrochemical oxidation of specifically designed DNA hexamers containing guanine has been studied in aqueous acetate buffet (pH 5) at a pyrolytic graphite electrode (PGE) by linear sweep voltammetry (LSV) Influence of the oligonucleotide composition and concentration was investigated It seems that short oligonucleotides containing guanine produce oxidation signals. which are sensitive to their structural properties Simple electrochemical techniques us may be useful tool for monitoring of structural changes of DNA.
Keywords: Linear sweep voltammetry; Oligonucleotides; Pyrolytic graphite electrode
Project no.: GA16-01625S (CEP), EF15_003/0000477
Funding provider: GA ČR, GA MŠk
Host item entry: XXXVIII. Moderní elektrochemické metody. Sborník přednášek, ISBN 978-80-905221-6-9

Institution: Institute of Biophysics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0297787

Permalink: http://www.nusl.cz/ntk/nusl-396386


The record appears in these collections:
Research > Institutes ASCR > Institute of Biophysics
Conference materials > Papers