Original title: Electrochemical Enzymatic Biosensors for Determination of Catecholamines in Flow Systems
Authors: Josypčuk, Bohdan ; Barek, J. ; Josypčuk, Oksana
Document type: Papers
Conference/Event: Moderní elektrochemické metody /39./, Jetřichovice (CZ), 20190520
Year: 2019
Language: eng
Abstract: Several biosensors (BS) based on flow enzymatic mini-reactors containing a mesoporous silica powder covered by enzyme laccase or tyrosinase were used for determination of L-DOPA, dopamine, noradrenaline, and adrenaline. The silica powder of MCM-41 with covalently bonded laccase was found to be the best reactor filling for the detection of catecholamines. Relative current response of such BS was 100 % for dopamine, 32.1 % for L-DOPA, 26.2 % for noradrenaline, and 0.71 % for adrenaline. The practical applicability of Lac-MCM41 biosensor was successfully verified by the determination of dopamine and noradrenaline in medical solutions for infusions.
Keywords: Catecholamines; Enzymatic biosensor; Flow analysis
Project no.: GA17-03868S (CEP)
Funding provider: GA ČR
Host item entry: XXXIX. Moderní elektrochemické metody. Sborník přednášek, ISBN 978-80-905221-7-6

Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available on demand via the digital repository of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0296750

Permalink: http://www.nusl.cz/ntk/nusl-395988


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Research > Institutes ASCR > J. Heyrovsky Institute of Physical Chemistry
Conference materials > Papers