Original title:
The role of mitochondrial SCoAS substrate-level phosphorylation in the bloodstream form \kur{T. brucei}
Authors:
HUSOVÁ, Michaela Document type: Bachelor's theses
Year:
2019
Language:
eng Abstract:
Mitochondrial metabolism of Trypanosoma brucei is considered highly reduced because of its dysfunctional electron transport chain and tricarboxylic acid cycle. But previously published paper suggests significant mitochondrial ATP pool created by substrate phosphorylation via succinyl coenzyme A synthetase, which plays crucial role in T. brucei survival. This thesis is therefore focused on substrate phosphorylation and on influence of succinyl coenzyme A synthetase heterodimer RNAi on T. brucei cells.
Keywords:
mitochondria; RNAi; substrate phosphorylation; succinyl coenzyme A synthetase; Trypanosoma brucei Citation: HUSOVÁ, Michaela. The role of mitochondrial SCoAS substrate-level phosphorylation in the bloodstream form \kur{T. brucei}. České Budějovice, 2019. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/52923