Original title:
Robust Cell Nuclei Tracking Using Gaussian
Mixture Shape Model
Authors:
Vičar, Tomáš Document type: Papers
Language:
eng Publisher:
Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií Abstract:
The life cell microscopic imaging is a standard approach for studying of cancer cell morphology and behaviour during some treatment. In the dense cell cultures, tracking each cell nucleus is challenging task due to cell overlap and interactions. Moreover, for time-lapse sequences (lasting typically 20-30 hours) the robust automatic cell tracking is needed. This paper describes new method for fluorescence nuclei tracking based on Gaussian mixture model (GMM), and additionally, GMM modification allowing application to the images is also introduced. Method is mainly designed for robustness - tracking the highest possible number of nuclei in the whole sequence. Proposed algorithm proved to by very reliable with 80% of correctly tracked nuclei.
Keywords:
Fluorescence nuclei images; Gaussian mixture model; nuclei tracking Host item entry: Proceedings of the 24th Conference STUDENT EEICT 2018, ISBN 978-80-214-5614-3
Institution: Brno University of Technology
(web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library. Original record: http://hdl.handle.net/11012/138302