Original title: Characterization of metabolic changes in hemocytes during the immune response in \kur{D. melanogaster}
Authors: KREJČOVÁ, Gabriela
Document type: Master’s theses
Year: 2018
Language: eng
Abstract: The aim of this thesis is to characterize metabolic changes in hemocytes during the immune response in D. melanogaster using in vivo markers as well as by measuring gene expression. The impact of the transcription factor HIF1 on the gene expression of glycolytic enzymes and its impact on the systemic metabolism was evaluated. The importance of HIF1 and LDH in the process of fighting against S. pneumoniae infection was tested as well.
Keywords: D. melanogaster; hemocytes; HIF1; metabolic switch; Polarization of macrophages; S. pneumoniae infection
Citation: KREJČOVÁ, Gabriela. Characterization of metabolic changes in hemocytes during the immune response in \kur{D. melanogaster}. České Budějovice, 2018. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/50420

Permalink: http://www.nusl.cz/ntk/nusl-376202


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Master’s theses