Original title:
Telomere length compensation mechanisms as players in longevity and stress adaptation of insects
Authors:
SÁBOVÁ, Michala Document type: Doctoral theses
Year:
2017
Language:
cze Abstract:
Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes that are important for genome stability and integrity. They are shortened with each cell cycle and during organismal aging. Although the most common telomere length compensation mechanism is the activity of a special reverse transcriptase, telomerase, in Drosophila telomeres are maintained by the retrotransposition of telomeric elements. In mammals, telomere length and telomerase activity can be influenced by lifestyle and the environmental conditions. This thesis is focused on activity of telomere length maintenance mechanism in insects in relation to aging and stress response.
Keywords:
aging; Apis mellifera; cost of reproduction; Drosophila melanogaster; honey bee; longevity; oxidative stress; telomerase; Telomeres; aging; Apis mellifera; cost of reproduction; Drosophila melanogaster; honey bee; longevity; oxidative stress; telomerase; Telomeres Citation: SÁBOVÁ, Michala. Telomere length compensation mechanisms as players in longevity and stress adaptation of insects . České Budějovice, 2017. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/40972