Original title:
Computer modelling of origin of arrhythmias in myocardial cell
Authors:
Brožková, K. ; Pásek, Michal Document type: Papers Conference/Event: International conference Engineering mechanics 2000, Svratka (CZ), 2000-05-15 / 2000-05-18
Year:
2000
Language:
eng Abstract:
This contribution presents the effect of changes of membrane channel conductivity on the origin of arrhythmias in cardiac cells. The simulations were performed for stimulation frequency 2Hz and compared with results for stimulation frequency 1Hz. It was confirmed that the increase of conductivity of ICa-channels and decrease of conductivity of IK1, INaCa and INaK channels induce single cell arrhythmias.
Keywords:
arrhythmias; carrdiac cell; quantitative modelling Project no.: CEZ:AV0Z2076919 (CEP), PP 20/7U Funding provider: ÚT AV ČR Host item entry: Engineering mechanics 2000, ISBN 80-86246-06-X
Institution: Institute of Thermomechanics AS ČR
(web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences. Original record: http://hdl.handle.net/11104/0107130