Original title: The impact of DNA methylation on the stability and dynamics of i-motif in the ILPR promoter region
Authors: ĎURINOVÁ, Eva
Document type: Bachelor's theses
Year: 2016
Language: eng
Abstract: The stability of i-motif structure in the promoter of the insulin gene was investigated by circular dichroism and single-molecule fluorescence resonance energy transfer. The main factor studied was the cytosine methylation and its location in the DNA sequence. Also the molecular crowding effect was examined. In addition, i-motif folding kinetics were investigated by the single molecule method.
Keywords: cytosine methylation; DNA folding; i-motif; ILPR; single-molecule FRET
Citation: ĎURINOVÁ, Eva. The impact of DNA methylation on the stability and dynamics of i-motif in the ILPR promoter region. České Budějovice, 2016. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/43714

Permalink: http://www.nusl.cz/ntk/nusl-253333


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses