Original title: Izolace obsahových látek Cannabis sativa a jejich biologický účinek
Translated title: Isolation of compounds from Cannabis sativa and their biological effect
Authors: Baranová, Zuzana ; Vespalcová, Milena (referee) ; Šmejkal,, Karel (advisor)
Document type: Bachelor's theses
Year: 2013
Language: slo
Publisher: Vysoké učení technické v Brně. Fakulta chemická
Abstract: [slo] [eng]
Predmetom záujmu tejto práce je tradičná a zároveň kontroverzná rastlina Cannabis sativa. V teoretickej časti je popísaná botanická stránka rastliny a jej súčasné medicínske formy. Podrobnejšie sú popísané doposiaľ izolované látky spolu s ich biologickou aktivitou. Experimentálna časť práce sa zaoberá izoláciou a identifikáciou látok chloroformovej frakcie extraktu získaného z tejto rastliny. Pre izoláciu boli použité chromatografické metódy –analytická a semipreparatívna HPLC. Získané látky boli identifikované pomocou UV a IR spektrofotometrie. Následne bol skúmaný biologický účinok získaných látok na vybraných druhoch mikroorganizmov. The object of this thesis is a traditional and also controversial plant Cannabis sativa. The theoretical part is focused on botanical side of this plant and its presently used medical forms. All previously isolated substances and their observed biological activity are described in detail. The experimental part of this thesis describes the isolation and identification of substances of the chloroform extract fraction obtained from this plant. Chromatographic methods were used for isolation – analytical and semipreparative HPLC. Obtained substances were identified using UV and IR spectrophotometry. Then the biological effect of obtained substances was observed on chosen microorganisms.
Keywords: biological effect; cannabinoids; Cannabis sativa; identification; isolation

Institution: Brno University of Technology (web)
Document availability information: Fulltext is available in the Brno University of Technology Digital Library.
Original record: http://hdl.handle.net/11012/25512

Permalink: http://www.nusl.cz/ntk/nusl-214084


The record appears in these collections:
Universities and colleges > Public universities > Brno University of Technology
Academic theses (ETDs) > Bachelor's theses