Original title:
Magnetic Beads-Based Electrochemical Techniques for DNA-Protein Interaction Monitoring
Authors:
Fojta, Miroslav ;
Pivoňková, Hana ;
Němcová, Kateřina ;
Horáková Brázdilová, Petra ;
Havran, Luděk ;
Orság, Petr ;
Vidláková, Pavlína ;
Macíčková-Cahová, Hana ;
Balintová, Jana ;
Hocek, Michal
Document type: Papers
Conference/Event: 31st International Conference on Modern Electrochemical Methods , Jetrichovice (CZ), 2011-05-23 / 2011-05-27
Year:
2011
Language:
eng
Abstract:
Electrochemical techniques, in connection with separation of nucleoprotein complexes at magnetic beads, are suitable for the monitoring of DNA-protein interactions. For the detection of complexes captured at the beads it is possible to utilize intrinsic electrochemical activity of the protein, intrinsic structure-selective signals of the DNA, or indicator DNA substrates tail-labeled with electroactive moieties.
Keywords:
DNA-protein interaction ;
Electrochemistry ;
Magnetic beads
Host item entry: MODERN ELECTROCHEMICAL METHODS XXXI, ISBN 978-80-254-9634-3
Institution: Institute of Biophysics AS ČR
(
web )
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0244016
Permalink: http://www.nusl.cz/ntk/nusl-180679
The record appears in these collections: Research > Institutes ASCR > Institute of Biophysics Conference materials > Papers