Original title: Using Anthraquinone Labeled Nucleotide Triphosphates for Electrochemical Analysis of DNA
Authors: Vidláková, Pavlína ; Balintová, Jana ; Horáková Brázdilová, Petra ; Havran, Luděk ; Orság, Petr ; Fojta, Miroslav ; Hocek, Michal
Document type: Proceedings
Conference/Event: 31st International Conference on Modern Electrochemical Methods, Jetrichovice (CZ), 2011-05-23 / 2011-05-27
Year: 2011
Language: eng
Abstract: Base-modified anthraquinone-nucleotide triphosphates were used for DNA labeling. Anthraquinone modified nucleotides were incorporated into DNA by primer extension with KOD polymerase. In cyclic and square wave voltammetry at HMDE or PGE antraquinone gave a well developed characteristic signal suitable for differentiation of the labeled DNA from unlabeled one.
Keywords: Anthraquinone; DNA; Electrochemical analysis

Institution: Institute of Biophysics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0244015

Permalink: http://www.nusl.cz/ntk/nusl-180678


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Research > Institutes ASCR > Institute of Biophysics
Conference materials > Proceedings