Original title: Spectroelectrochemistry of Flavonolignans and their DNA-binding Copper Complexes
Authors: Sokolová, Romana ; Kubala, M. ; Vavříková, E. ; Ulrichová, J. ; Křen, Vladimír ; Vacek, J.
Document type: Papers
Conference/Event: Pracovní setkání fyzikálních chemiků a elektrochemiků /13./, Brno (CZ), 2013-05-29 / 2013-05-30
Year: 2013
Language: eng
Abstract: The oxidation of flavonolagnan silybin and its selected derivatives was studied on glassy carbon electrode in aqueous environment by means of cyclic voltammetry, in situ UV/VIS spectroelectrochemistry and absorption spectrometry. The oxidation mechanism of flavonolignans and their complexion with copper was investigated under anaerobic conditions. The acquired results were interpreted in context of protective (antioxidant) and DNA-binding (prooxidant) properties of flavonolignans and their transition metal complexes.
Keywords: copper complexes; flavonolignans; spectroelectrochemistry
Project no.: M200401201
Funding provider: Rada Programu interní podpory projektů mezinárodní spolupráce AV ČR
Host item entry: XIII. Pracovní setkání fyzikálních chemiků a elektrochemiků. Sborník příspěvků, ISBN 978-80-7375-757-1

Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0221660

Permalink: http://www.nusl.cz/ntk/nusl-155290


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Research > Institutes ASCR > J. Heyrovsky Institute of Physical Chemistry
Conference materials > Papers