Original title: Iron-Sulfur Cluster Assembly in Trypanosoma brucei
Authors: HAINDRICH, Alexander Christoph
Document type: Bachelor's theses
Year: 2013
Language: eng
Abstract: In this thesis we investigated genes of the Cytosolic Iron sulfur cluster assembly (CIA) pathway in T. brucei procyclic and blood-stream form for their possible functional redundancy. For this, RNAi double knockdown plasmids were generated containing knockdown partners which were selected based on the proposed model of the CIA pathway in S. cerevisiae. The generated plasmids were transfected into T. brucei cells, and growth effects on the transfectants upon tetracycline induced RNAi was measured.
Keywords: CIA; Iron Sulfur Cluster; RNAi; Trypanosoma brucei
Citation: HAINDRICH, Alexander Christoph. Iron-Sulfur Cluster Assembly in Trypanosoma brucei. České Budějovice, 2013. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/27471

Permalink: http://www.nusl.cz/ntk/nusl-154242


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses