Original title: Localization of Lyme disease spirochetes \kur{Borrelia burgdorferi} in ticks \kur{Ixodes ricinus}
Authors: STRNAD, Martin
Document type: Master’s theses
Year: 2013
Language: eng
Abstract: Lyme disease is the most common vector-borne infection in the Western world with an annual incidence usually in excess of 100 cases per 100 000 people in temperate areas of the United States and Europe. Same as other infectious diseases, Lyme borreliosis wreaks havoc on the host they have invaded. B. burgdorferi, the causative agent of this disease, circulates among wildlife vertebrate hosts and Ixodes tick vectors but may sometimes infect humans. Its natural enzootic cycle usually occurs as follows: The larval/nymphal stage tick feeds on an infected host. During this engorgement, the spirochetes reach the tick gut and stay confined to it. After the tick molts into the next developmental stage, it finds a second host. The new bloodmeal triggers the spirochetes to multiply within the gut and traverse the gut endothelium in a highly organized manner. They finally disseminate through the hemocoel up to the tick salivary glands and into the new host. We studied whether B. burgdorferi is capable of reaching the tick salivary glands during the first infective feeding period in uninfected ticks.
Keywords: Borrelia burgdorferi; fluorescence and electron microscopy; in-vitro feeding; Ixodes ricinus
Citation: STRNAD, Martin. Localization of Lyme disease spirochetes \kur{Borrelia burgdorferi} in ticks \kur{Ixodes ricinus}. České Budějovice, 2013. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/27836

Permalink: http://www.nusl.cz/ntk/nusl-153083


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Master’s theses
 Record created 2013-05-01, last modified 2023-01-15


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