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Multi-function Cultural Centre "Creative City" in Brno
Macková, Eliška ; Vaněk, Petr (referee) ; Vojtová, Lea (advisor)
The diploma thesis Multifunctional Culture Centre ‘Creative City’ Brno deals with the architectural study of rebuilding and extension of the former prison building in Bratislavská and Soudní street in Brno for cultural, social and commercial purposes. The project includes a new use of the existing building for creative industries, commercial activities and services. There are apartments in the new extension. The parking places are situated below the ground level in the northern part of the complex. The building complex creates a pleasant environment contributing the creativity.
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Yoga exercises and its influence on feelings of preschool teachers in the context of psychological workload.
Macková, Eliška ; Dvořáková, Hana (advisor) ; Kainová, Lucie (referee)
The aim of this work is to find out whether the feelings of preschool teachers will change from the psychological load because of yoga exercises. Preschool teachers are exposed to many factors, which are burdensome for their mental health. Therefore, there is a need to pay attention to their mental health. The medium of mental hygiene in this thesis is yoga exercise, which also includes relaxation. There were three research methods used to create the research of this diploma thesis. The first one used was the Meister's standardized questionnaire. This questionnaire was used to determine the work related psychological burden of preschool teachers. Subsequently the method of semi-structured interview with five preschool teachers was used. These teachers also participated in a quasi-experiment. The main method is a four week quasi-experiment with 5 preschool teachers. These preschool teachers practiced yoga exercises and relaxation according to video lessons for 4 weeks. The output data were again provided by Meister's standardized questionnaire and a semi-structured interview with all 5 respondents. These two methods recorded the state before and after the experiment. The questionnaire survey revealed that most kindergarten teachers feel a 3rd degree of psychological stress in the performance of...
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Multi-function Cultural Centre "Creative City" in Brno
Macková, Eliška ; Vaněk, Petr (referee) ; Vojtová, Lea (advisor)
The diploma thesis Multifunctional Culture Centre ‘Creative City’ Brno deals with the architectural study of rebuilding and extension of the former prison building in Bratislavská and Soudní street in Brno for cultural, social and commercial purposes. The project includes a new use of the existing building for creative industries, commercial activities and services. There are apartments in the new extension. The parking places are situated below the ground level in the northern part of the complex. The building complex creates a pleasant environment contributing the creativity.
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In vitro assessment of antiproliferative effects of novel intracellular iron chelators
Macková, Eliška ; Kvasničková, Eva (referee) ; Šimůnek, Tomáš (advisor)
Charles rnáversáty án mrague caculty of mharmacy án eradec hrálové aeéartment of Báochemácal pcáences CandádateW bláška jacková puéervásorW aocK mharmarK Tomáš ŠámůnekI mhKaK Tátle of dáéloma thesásW In vitro assessment of antáéroláferatáve effects of novel ántracellular áron chelators Aroylhydrazones are trádentate láéofálác áron chelators wáth very good entry to cellsK fn our éreváous exéerámentsI salácylaldehyde ásonácotánoyl hydrazone EpfeFI has shown very ánterestáng antáoxádant and antáéroláferatáve effácáencáes K eoweverI áts major dásadvantage ás low stabáláty caused by a fast hydrolysás of hydrazone bondK ThereforeI the seráes of náne new analogues of pfe deráved from aromatác ketones has been synthetázed at the aeéartment of fnorganác and lrganác Chemástry of our facultyK lur recent study extends our éreváous exéeráments wáth these substances and examánes éotentáal use of these new aroylhydrazones án antátumour treatmentK The breast adenocarcánoma cell láne jCc-T and human éromyelocytác leukemáa cell láne eiSM were usedK mroláferatáon tests took TO hoursI when cells were exéosed to actáon of substances or theár combánatáons ptatástácally ságnáfácant antáéroláferatáve actáváty was noted án all new chelators at the both cell lánesK te coméared the fC5M values of each chelator to cancer cell...
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