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The process of contracting and change of public procurement contract
Kubeš, Jiří ; Eichlerová, Kateřina (advisor) ; Horáček, Tomáš (referee)
79 Abstract The method of entering into a contract in public tenders according to Act. No. 134/2016 Coll. is a civil contractual process with a high degree of formalization and legal regulation. This makes it different from the general contractual process in civil law. The first chapter of this thesis is devoted to the analysis of public tenders in terms of setting up the legal framework. It goes into a conclusion that contractual process in public tender is part of the civil law with the subsidiary use of civil law rules, especially the Civil Code. The second chapter deals with a contractual process in a public tender itself. The process is divided into two phases - a precontractual phase and contractual phase. The precontractual phase includes procedures of the public tender that determine the clarification of content of the contract and the range of contractors. The contractual phase contains mainly the actual entering into a contract with successful tenderer. The chapter describes the specificity of the contractual process in a public tender since the announcement of the tender up to the actual entering into a contract. These specificities are introduced in relation to the open procedure being used in upper-tier mode. At the end of the chapter, there is a comparison with other types of proceedings and...
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"Eastern Europe" in the Mental Map of an English Traveller from the 16th to the 18th Century
Radiměřská, Božena ; Klusáková, Luďa (advisor) ; Kubeš, Jiří (referee) ; Křížová, Markéta (referee)
"Eastern Europe" in the Mental Map of an English Traveller from the 16th to the 18th Century Abstract The thesis aims to interpret the early modern English/British travel writings about (Central) Eastern Europe. It results in the reconstruction of mental maps of the selected travellers with regard to a typology (merchants, professionals, intellectuals, clergymen, and women). The special attention is paid to the images of marginality, such as inconvenience and danger, ignorance and backwardness, exaggeration and pomp, former splendour and present lamentation, pleasant and unpleasant landscape. The primary sources comprise a selection of fifteen travel writings which are read and interpreted with respect to the development of the genre and to the broader cultural and historical context. The covering concept is a mental map conceived as an imaginary representation of space and as a tool for cultural orientation and self-identification. The reconstruction of the mental maps is performed in four steps. Firstly, by defining the subject (a traveller) within the typology. Secondly, the landmarks (centres) in the mental maps are reconstructed. Thirdly, the images of marginality are presented. Finally, the mental maps are concluded. Methodologically, the thesis is based on the interpretation and language analysis of...
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Stephan Wilhelm Kinsky as the Imperial Envoy in Russia of Peter the Great, 1721 - 1722. Acta Legationis Moscoviticae or Diplomatic Relations as a Early Modern Source.
Hrebiková, Anežka ; Hojda, Zdeněk (advisor) ; Kubeš, Jiří (referee)
The aim of presented dissertation is the analysis of diplomatic relations Acta Legationis Moscoviticae. These relations are reports, which were sented to Vienna by imperial envoy Stephan Wilhelm Kinsky during his activity on the tsarist court in Sankt-Peterburg and Moscow in 1721-1722. On the basis of this source, the main interest is concentrated on the course of Kinskys diplomatic mission and on tasks, which he should fulfil as the envoy. The dissertation, beside other things, puts the task to evaluate diplomatic relations as the source for history of diplomacy and history of international relations. In the dissertation is introduced life and career of Stephan Wilhelm Kinsky and his personality. The attention is also paid to the most importants measures of Peter I. in defined period, mainly the concluding of Treaty of Nystad, proclaiming Peter as Emperor of All Russia and issue of manifesto about successory. The dissertation also tries to depict the turning period in Russian Empire after the end of Great Northern War and focuses on the atmosphere of court society at that time. The dissertation puts the question, which of points of instructions from Vienna court were fulfilled or not fulfilled by bohemian nobleman. The Kinskys mission is approached as the part of process of negotiation about...
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Spanish Embassy in Prague under don Baltasar De Zúñiga (1608-1617)
Bardoňová, Martina ; Šedivá Koldinská, Marie (advisor) ; Kubeš, Jiří (referee) ; Marek, Pavel (referee)
The present work is a contribution to the history of the Early modern diplomacy and early modern diplomatic practics. The subject of this work is the diplomatic misson of Baltasar de Zúñiga at imerial court (1608-1617). The study focuses on description of embassy functioning based on an analyses of official documents produced by the embassy itself, which were in several instances complemented by some of the documents produced by the Spanish governmental bureucracy such as, instructions, credentials, consultas or correspondence addressed to the hands of ambassador Baltasar de Zúñiga. As such, the present study is a kind of introspection, because it shows the functioning of a diplomatic mission from inside. The aim is to aswer the following questions. What part of the day-to-day work of a specific embassy could be seen, and controled by a sending government. How the chosen sources represent the basis of the Spanish policy in the Holy Roman Empire, the instruments used to increase the reputation of the Spanish king and the reputation of the ambassaror himself.
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Combined treatment of advanced head and neck cancer with radiotherapy and cycooxygenase-2 inhibitors (phase I study)
Halámka, Magdalena ; Petera, Jiří (advisor) ; Soumarová, Renata (referee) ; Kubeš, Jiří (referee)
Combined treatment of advanced head and neck cancer with radiotherapy and cycooxygenase-2 inhibitors (phase I study) This paper describes the course and presents the outcomes of a original phase I study of combined treatment of advanced head and neck cancer using standard radiotherapeutic technique and COX2 inhibitor (Celebrex) as a potentiating agent. The primary goal of the study was identifying of the maximum tolerated dose of Celebrex for the purpose of further clinical investigation. In the theoretical introduction I present data on the incidence and mortality of HaN cancer worldwide and in the Czech republic, further preclinical data justifying use of Celebrex in combined treatment with radiotherapy. Special emphasis was put on presentation of local data systematically gained in Clinic of Oncology in Ostrava where this study has been conducted. These data include an overview of incidence, mortality, therapeutic methods and treatment toxicity profiles. Since the phase I study as such does not include comparison with control patient group, it is necessary to be aware of local standards. This is the background to establish inclusion criteria for patient recruitment, toxicity evaluation and setting maximum tolerance dose criteria. This study furthermore investigates expression of COX2 in tumor tissue and...
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Hyperthermia in the treatment of locally advanced or recurrent breast cancer
Pešulová, Andrea ; Kubeš, Jiří (advisor) ; Zapletal, Radek (referee)
As the subject of my bachelor's thesis I have selected hyperthermia as an instrument in the treatment of local advanced or recurrent breast cancer. In separate chapters I describe the anatomy, epidemiology, aetiological factors, clinical symptoms, diagnostic screening, and principal characteristics of local advanced or recurrent carcinoma, their TNM classification and therapeutic options. The bulk of my work is devoted to hyperthermia. I describe hyperthermia as an anti-tumour therapeutic modality, which utilizes the warming of tissue to a temperature of 40 - 44 řC. Hyperthermia is deployed locally, partially or generally (whole body). It is combined with other treatment possibilities, such as radiotherapy, chemotherapy, etc. In particular cases of advanced or recurrent tumours, treatment results are much improved by the combined use of hyperthermia with radiotherapy or chemotherapy. I go on to describe the history of hyperthermia, the mechanisms for its effectiveness in terms of tissue and immunology and DNA repair, the technical equipment necessary for its implementation, results of clinical trials, and side-effects. Hyperthermia is deployed in a small number of centres in the Czech Republic, namely Hradec Králové and Prague. In Hradec Králové, ultrasound warming is used, while the Prague centre uses...
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Immunomodulation effects of the hyperthermia in cancer treatment
Kubeš, Jiří ; Rosina, Jozef (advisor) ; Vrba, Jan (referee) ; Zámečník, Jiří (referee)
The dissertation thesis "Immunomodulation effects of the hyperthermia in cancer treatment" relates on the hyperthermia as evolving method of the cancer treatment. The first part describes hyperthermia in general, especially physical principles of the heating, the equipment necessary for clinical practice of the hyperthermia, basic effects in biological tissues, clinical indications and results. The second part is brief review of mechanisms antitumor immunological response, with emphasis on antigenicity of tumor cells and effector cells in antitumor response.
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Přibík Jeníšek z Újezda, clerk from the time after the White mountain battle
Bacík, Radek ; Kubeš, Jiří (referee) ; Čechura, Jaroslav (advisor)
Přibík Jeníšek from Újezd (1580?-1651) belonged to small knight aristocrats, who were in the time before the battle of White mountain innumerable. He was born in the west Bohemian fortress Svrčovec as the fourth of the five brothers. His chances to get the good inheritance were very poor. Thaťs why he looked for alternative way to become socially more important. He found as the best the career of clerk in the Bohemian provincial machinery of government. Under the supervision of his uncle Jan from Klenova and Janovice, the highest scrivener, he affected at first as counselor of the court of the highest office of the burgraver of Prague (1611- 1616) and then in the Office of Tabulare Terrae as the minor scrivener (1616-1618). During this time he was able to follow the exacerbation of the situation between the monarch and the noblemen which was denominationally divided.
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Use of Wolfram Alpha - interactive computional engine for financial mathematics
KUBEŠ, Jiří
This bachelor's thesis analyzes possibillities of using application Wolfram Alpha in financial mathematics. The work presents selected products created by Wolfram Research. Readers get to know the interface of Wolfram Alpha. Theoretical part of the work introduces the readers to the matters of financial mathematics. The work shows general use of Wolfram Alpha for financnial mathematics. Practical part deals with selected examples of financial mathematics and theirs solutions in Wolfram Alpha. Partial aim of this thesis is to create paper, which can be used as support for teachers of finan-cial mathematics.
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