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Pathophysiological and clinical aspects of cardiac dyssynchrony in children and adolescents
Kovanda, Jan ; Janoušek, Jan (advisor) ; Bulava, Alan (referee) ; Klásková, Eva (referee)
Pathophysiological and clinical aspects of cardiac dyssynchrony in children and adolescents Electromechanical dyssynchrony is an important factor in the development of heart failure. It is caused by abnormal activation of the working myocardium in case of bundle branch block or ventricular pacing. Asymmetric hypertrophy of the affected ventricle develops together with its dilatation and reduced function and fulfils the picture of dyssynchronous cardiomyopathy. The development of dyssynchronopathy can be prevented by careful selection of the permanent pacing site and treated by cardiac resynchronization therapy. One of the aims of this work was to compare clinical and echocardiographic findings in patients paced from the left-ventricular apex with the healthy population. Using a retrospective cross-sectional study, we have proved that left ventricular function is not adversely affected in long-term follow-up. Another aim of the study was to evaluate the long-term results of resynchronization therapy of the systemic ventricle in patients with congenital heart defects. Using a retrospective study, we have described an acceptable long-term survival at the price of relatively frequent complications. We were extensively working on a new method of resynchronization of the right subpulmonary ventricle in...
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Occupation of a set time of random walks
Janoušek, Jan ; Hlubinka, Daniel (advisor) ; Karafiátová, Iva (referee)
This bachelor's thesis aims to analyse random walks, emphasizing symmetric random walks. We focus mainly on the occupation of a set times. In this thesis, we find the distribution of maxima and minima, the probability of return to the origin, and the probability of first return to the origin. Then we see the arcsine laws and the probability of spending a given amount of time on the positive and the negative side. We generalize this not only for the positive and negative sides but for any given interval. At the end of the thesis, we create statistical tests based on the theoretical distribution derived in the thesis. 1
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HSR (RS42) Design of the Track Section Nova Ves Junction - Louny
Losenický, Miloš ; Janoušek, Jan (referee) ; Dušek, Erik (advisor)
The aim of bachelor thesis is to design a new high-speed line between Nova ves – railway station Louny. Route of HSR is designed only for passenger traffic and for track speed 250 kph. The track section starts by the road II/118. The thesis includes the design of the track junction in front of the railway station Louny with the modification of the existing railway lines and including the design of the exit from the HSR.
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Hellenistic Syncretism with Regard to the Egyptian Cult
Hanzelková, Lena Magdala ; Janoušek, Jan (advisor) ; Hruška, Blahoslav (referee)
The submitted research work concerns with Hellenistic syncretism as a religious phenomenon that widened approach and reception of described deities in a given period, all that with emphasis on Egyptian cult. These deities are compared with other gods originating in Greek region or domesticated therein. Particular attention is paid to goddess Isis, which had considerable influence on religious, and herewith as well a cultural world of Hellenism. An outstanding chapter applies to mysteries, especially those connected with Isis.
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Hermes - The God Between the Human and Divine Worlds and His Metamorfoses in Time
Špillingová, Eva ; Janoušek, Jan (advisor) ; Hruška, Blahoslav (referee)
The main theme of this thesis is the figure of the Greek god Hermes and the changes in its understanding, spanning from the archaic images to the character of Mercury in the Hermetic tradition and alchemy. Attention is paid to Hermes' transformation into an Olympian god which he underwent in the works of Homer. At the same time his godly child characteristics are being discussed as well as his relations to some. other gods of Olympic pantheon. Another important change in the understanding of Hermes' figure can be observed during the period of the Hellenistic religious syncretism, the time in which the Greek culture and its gods were exposed to the oriental and Egyptian cults. The concluding part of the thesis discusses the transformation of Hermes into the character of Mercury of the alchemists, which enabled him to be the only one of the Greek gods to survive until the 17th century.
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The Presentation of Transforming Attributes in SQL for Data Governance Support
Bartoš, Michal ; Janoušek, Jan (advisor) ; Kopecký, Michal (referee)
This thesis examines extraction of attributes' transformation descriptions from Oracle SQL scripts and possibilities of their presentation to users. This thesis com- pares several variants of output format. Then it describes details of construction for the chosen format and choices that led to it. One of the main decisions was the choice of input data structures: abstract syntax tree and dataflow graph. Those data structures provide initial analysis of input SQL scripts but they also strongly influence the rest of processing. Results of this thesis were verified by prototype implementation in software Manta. The prototype confirmed suitability of the chosen approach for convenient presentation to users. 1
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Development of cardiovascular system function in patients with a functionally single ventricle
Materna, Ondřej ; Janoušek, Jan (advisor) ; Klásková, Eva (referee) ; Urbanová, Zuzana (referee)
Development of cardiovascular system function in patients with a functionally single ventricle. Abstract Total cavopulmonary connection (TCPC) is the only possible surgical palliative procedure in patients with a functionally single ventricle. It consists of the stepwise anastomosis of both caval veins with pulmonary arteries, creating a unique situation of so-called Fontan circulation, where the separation of the pulmonary and systemic circuit is traded for chronically elevated systemic venous pressure and impaired cardiac output increase during exercise. We aimed to evaluate long-term results and development of exercise capacity in the population of patients with TCPC in the Czech Republic, possible predictors of their survival and functional outcome, as well as analysis of permanent cardiac resynchronization as one of the new treatment options for dysfunction of the single ventricle. We present a retrospective study of all consecutive patients in the Czech Republic identified in the nationwide single-centre institutional database and matched with the National Death Registry and Cardiovascular Intervention Registries. We proved that overall mean survival probability until composite end-point of death, TCPC take- down or indication for a heart transplant was 92.9 % at 20 years after the operation. TCPC...
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Design of the North Junction from Hranice na Morave to HSR Line
Gelová, Zuzana ; Janoušek, Jan (referee) ; Dušek, Erik (advisor)
The aim of this master’s thesis is the design of railway junction from high-speed rail RS1 Bohumín – Přerov to railway station Hranice na Moravě at a speed 160 of kph. The design has been developed with minimisation of land occupation and the minimisation of engineering structures. The next aim is the design of two pairs of railroad switch on the high-speed rail. Part of the thesis is the design of the railway substructure, railway superstructure and track drainage.
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