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Název:
Improvement of an unbaffled stirred tank mixing characteristics using variable speed impeller
Autoři: Gebouský, Ondřej ; Haidl, Jan ; Bodnár, J. ; Pivokonský, Martin
Typ dokumentu: Příspěvky z konference
Konference/Akce: Topical Problems of Fluid Mechanics 2024, Prague (CZ), 20240221
Rok: 2024
Jazyk: eng
Abstrakt: Unbaffled mixing tanks with magnetically driven impellers are increasingly used in biotechnological and pharmaceutical industries, combining the benefits of a closed, sterile environment with easy equipment cleanability. On the other hand, missing internals, such as baffles or cooling coils, have an adverse effect on the equipment mixing characteristics, namely the batch\nhomogenization time. In our previous research, we uncovered that the eccentricity and inclination of the impeller – both employed routinely to enhance the mixing characteristics of unbaffled vessels – are not fully effective in the suppression of central vortex formation resulting in the increase in the homogenization time. In this work, we propose a simple solution to counteract the central vortex formation – a periodical variation of impeller rotational speed. This approach destabilizes the central vortex, significantly reducing homogenization time while maintaining the benefits of the original unbaffled setup. This innovation can seamlessly integrate into existing industrial setups, promising efficiency gains for biotech and pharmaceutical production.
Klíčová slova: mixing time improvement; unbaffled mixing tanks; variable rotational speed; vortex destabilization
Číslo projektu: StrategieAV21/20, AP2201
Poskytovatel projektu: AV ČR, AV ČR
Zdrojový dokument: Topical Problems of Fluid Mechanics, ISBN 978-80-87012-88-8, ISSN 2336-5781
Poznámka: Související webová stránka: http://www2.it.cas.cz/fm/im/im/proceeding/2024/8
Instituce: Ústav pro hydrodynamiku AV ČR (web)
Informace o dostupnosti dokumentu: Dokument je dostupný v repozitáři Akademie věd.
Původní záznam: https://hdl.handle.net/11104/0353398
Trvalý odkaz NUŠL: http://www.nusl.cz/ntk/nusl-614324
Autoři: Gebouský, Ondřej ; Haidl, Jan ; Bodnár, J. ; Pivokonský, Martin
Typ dokumentu: Příspěvky z konference
Konference/Akce: Topical Problems of Fluid Mechanics 2024, Prague (CZ), 20240221
Rok: 2024
Jazyk: eng
Abstrakt: Unbaffled mixing tanks with magnetically driven impellers are increasingly used in biotechnological and pharmaceutical industries, combining the benefits of a closed, sterile environment with easy equipment cleanability. On the other hand, missing internals, such as baffles or cooling coils, have an adverse effect on the equipment mixing characteristics, namely the batch\nhomogenization time. In our previous research, we uncovered that the eccentricity and inclination of the impeller – both employed routinely to enhance the mixing characteristics of unbaffled vessels – are not fully effective in the suppression of central vortex formation resulting in the increase in the homogenization time. In this work, we propose a simple solution to counteract the central vortex formation – a periodical variation of impeller rotational speed. This approach destabilizes the central vortex, significantly reducing homogenization time while maintaining the benefits of the original unbaffled setup. This innovation can seamlessly integrate into existing industrial setups, promising efficiency gains for biotech and pharmaceutical production.
Klíčová slova: mixing time improvement; unbaffled mixing tanks; variable rotational speed; vortex destabilization
Číslo projektu: StrategieAV21/20, AP2201
Poskytovatel projektu: AV ČR, AV ČR
Zdrojový dokument: Topical Problems of Fluid Mechanics, ISBN 978-80-87012-88-8, ISSN 2336-5781
Poznámka: Související webová stránka: http://www2.it.cas.cz/fm/im/im/proceeding/2024/8
Instituce: Ústav pro hydrodynamiku AV ČR (web)
Informace o dostupnosti dokumentu: Dokument je dostupný v repozitáři Akademie věd.
Původní záznam: https://hdl.handle.net/11104/0353398
Trvalý odkaz NUŠL: http://www.nusl.cz/ntk/nusl-614324
Záznam vytvořen dne 2024-05-12, naposledy upraven 2024-05-12.