Original title: Occurrence of the cALAs gene in the BCCO Actinomycetes collection and cultivation improvements for the overproduction of secondary metabolites in soil associated Actinomycetes
Authors: PULFERER, Lisa
Document type: Bachelor's theses
Year: 2021
Language: eng
Abstract: Metabolites produced by Bacteria are known to have a wide range of biological activities, which are applied in various fields, like medicine. Most of them are synthesized by members of the group Actinomycetes, in particular from the genus Streptomyces. This thesis deals with the screening process of various Streptomyces strains for a specific gene which is involved in the synthesis of a manumycin-like secondary metabolite. Another aspect discussed here is how the addition of agar to the fermentation media and the pH value can influence the synthesis of bioactive metabolites. To determine the effectiveness of the metabolites various experiments were conducted.
Keywords: Actinomycetes; antibacterial activity; cyclizing 5-aminolevulinate synthase; Kutzneria; secondary metabolites; Streptomyces
Citation: PULFERER, Lisa. Occurrence of the cALAs gene in the BCCO Actinomycetes collection and cultivation improvements for the overproduction of secondary metabolites in soil associated Actinomycetes. České Budějovice, 2021. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/59358

Permalink: http://www.nusl.cz/ntk/nusl-515503


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses