Original title: The effect of Ixodes ricinus tick serpin on the cytotoxic function of natural killer cells
Authors: FIŠEROVÁ, Simona
Document type: Master’s theses
Year: 2020
Language: eng
Abstract: The aim of my thesis was the functional characterization of IRS-4 from Ixodes Ricinus. Particularly the effect of IRS-4 on cytotoxic activity of NK cells was analysed. First, the optimization of calcein-AM release method, which was used for this analysis, was performed. Afterwards, the method was used for the measurement of the cytotoxic activity of NK cells. Moreover, the effect of tick serpin on the activation of NK cells by measuring the cytokine production IFN- was examined.
Keywords: calcein-AM; IRS-4; natural killer cells (NK); NK cytotoxicity; serpins
Citation: FIŠEROVÁ, Simona. The effect of Ixodes ricinus tick serpin on the cytotoxic function of natural killer cells. České Budějovice, 2020. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/56042

Permalink: http://www.nusl.cz/ntk/nusl-514135


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Master’s theses