Original title: Functional analysis of circadian clock gene timeless in temperature compensation mechanism
Authors: SINGH, Samarjeet
Document type: Doctoral theses
Year: 2020
Language: eng
Abstract: This thesis is focussed on investigating the role of the circadian clock gene timeless in the temperature compensation mechanism in Drosophila melanogaster. To conduct the studies presented in this thesis advanced gene editing technique, CRISPR/Cas9, was used to target timeless and to create a variety of mutations. Application of various reverse genetics tools and behavioural methods described here contributed to the elucidation of timeless role in temperature compensation of the circadian clock.
Keywords: circadian clock; CRISPR/Cas9; Drosophila melanogaster; Reverse genetics; screening; temperature compensation; timeless
Citation: SINGH, Samarjeet. Functional analysis of circadian clock gene timeless in temperature compensation mechanism. České Budějovice, 2020. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/36693

Permalink: http://www.nusl.cz/ntk/nusl-513430


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Doctoral theses