Original title: Mechanism of dsRNA virus replication: cloning, production and structural characterization of N-terminal domain of sigmaNS
Authors: KOTOUNOVÁ, Eliška
Document type: Bachelor's theses
Year: 2019
Language: eng
Abstract: Avian reovirus is an important pathogen, which causes substantial losses in poultry industry. NS protein is essential for the virus replication, however, the mechanism and assortment of genomic segments during virus replication is yet not well understood. The structure of NS is not known as previous attempts at crystallization yielded non-diffracting crystals due to the flexible regions in the molecule. This thesis deals with the production and purification of the N-terminal domain of NS, which lacks the exposed flexible region.
Citation: KOTOUNOVÁ, Eliška. Mechanism of dsRNA virus replication: cloning, production and structural characterization of N-terminal domain of sigmaNS. České Budějovice, 2019. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/52814

Permalink: http://www.nusl.cz/ntk/nusl-395126


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Bachelor's theses