Original title: Characterisation of \kur{Drosophila melanogaster} mutated for all genes of the Sirtuin family
Authors: PEKÁČOVÁ, Aneta
Document type: Master’s theses
Year: 2019
Language: eng
Abstract: The aim of my study was to create a Drosophila line lacking the expression of all Sirtuin genes, check its developmental phenotype and characterise its response in stress conditions. The flies had bigger weight than controls, they had decreased fertility and fecundity and they developed more slowly. They showed a trend towards increased resistance to chill coma, but they did not show a significant difference in starvation or oxidative stress assay. Its effect on lifespan is being investigated.
Keywords: characterisation; drosophila; mutation; sirtuin
Citation: PEKÁČOVÁ, Aneta. Characterisation of \kur{Drosophila melanogaster} mutated for all genes of the Sirtuin family . České Budějovice, 2019. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

Institution: University of South Bohemia in České Budějovice (web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia.
Original record: http://www.jcu.cz/vskp/55794

Permalink: http://www.nusl.cz/ntk/nusl-394803


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Universities and colleges > Public universities > University of South Bohemia in České Budějovice
Academic theses (ETDs) > Master’s theses