Original title: Potent anti-spasticity and anti-nociceptive effect of subpial GAD65 and VGAT gene delivery in rat and mice
Authors: Maršala, M. ; Tadokoro, T. ; Hernandez, M. B. ; Navarro, M. ; Maršala, S. ; Miyanohara, A. ; Juhás, Štefan ; Juhásová, Jana ; Platoshyn, O.
Document type: Papers
Conference/Event: Animal Models of Neurodegenerative Diseases /4./, Liblice (CZ), 20171022
Year: 2017
Language: eng
Abstract: In previous studies we have developed a novel spinal subpial (SP) AAV delivery technique in adult mice, rats and minipigs. Using this technique we have demonstrated potent and wide-spread transgene (GFP) expression in spinal white and gray matter after a single SP bolus of AAV9-UBI-GFP.
Keywords: mouse; rat
Project no.: LO1609 (CEP)
Funding provider: GA MŠk
Host item entry: The 4th Animal Models of Neurodegenerative Diseases

Institution: Institute of Animal Physiology and Genetics AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0280231

Permalink: http://www.nusl.cz/ntk/nusl-371498


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Research > Institutes ASCR > Institute of Animal Physiology and Genetics
Conference materials > Papers