Original title: Voltammetric Determination of Tumor Biomarkers using Flow Injection Analysis with Amperometric Detection
Authors: Makrlíková, Anna ; Matysik, F.-M. ; Barek, J. ; Vyskočil, V.
Document type: Papers
Conference/Event: International Students Conference ”Modern Analytical Chemistry” /13./, Prague (CZ), 20170921
Year: 2017
Language: eng
Abstract: Three tumor biomarkers (homovanillic acid, vanillylmandelic acid,\nand 5-hydroxyindole-3-acetic acid) have been determined by flow\ninjection analysis with amperometric detection at screen-printed\ncarbon electrodes in optimum medium of Britton-Robinson buffer\n(0.04 mol l-1, pH = 2.0). Dependences of the peaks current on the\nconcentration of biomarkers were linear in the tested concentration\nregion from 0.05 to 100 mu mol l-1, with the limits of detection of\n0.065 mu mol l-1 for homovanillic acid, 0.053 mu mol l-1 for vanillylmandelic\nacid, and 0.033 mu mol l-1 for 5-hydroxyindole-3-acetic acid (calculated\nfrom heights), and 0.024 mu mol 1-1 for homovanillic acid,\n0.020 mu mol l-1 forvanillylmandelic acid, and 0.012 mu mol l-1 for 5-hydroxyindole-3-acetic acid (calculated from areas), respectively.
Keywords: 5-hydroxyindole-3-acetic acid; flow injection analysis; homovanillic acid
Host item entry: Proceedings of the 13th International Students Conference ”Modern Analytical Chemistry”, ISBN 978-80-7444-052-6

Institution: J. Heyrovsky Institute of Physical Chemistry AS ČR (web)
Document availability information: Fulltext is available on demand via the digital repository of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0275772

Permalink: http://www.nusl.cz/ntk/nusl-367390


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