Original title: Spliceosomal Assembly on Precursor mRNA Takes Place in the Nuclear Speckles
Authors: Melčák, Ivo ; Cermanová, Štěpánka ; Raška, Ivan
Document type: Papers
Conference/Event: MENDEL 2000, Brno (CZ), 2000-07-19 / 2000-07-23
Year: 2000
Language: eng
Abstract: Nuclear speckles (speckles), enriched in splicing factors, form a distict nuclear compartment within the interchromatin space. It has been schown to serve vicinal active genes as a reservoir of splicing factors.We show that (pre-)spliceosomal assemblyy on pre-mRNA is associated with the speckles in HeLa cells.
Project no.: VS96129 (CEP), GA304/00/1481 (CEP), GA302/99/0587 (CEP), 049949/Z/97/Z/JMW/JPS/CG, CEZ:AV0Z5039906 (CEP)
Funding provider: GA MŠk, GA ČR, GA ČR, Wellcome Trust grant
Host item entry: MENDEL 2000

Institution: Institute of Experimental Medicine AS ČR (web)
Document availability information: Fulltext is available at the institute of the Academy of Sciences.
Original record: http://hdl.handle.net/11104/0070417

Permalink: http://www.nusl.cz/ntk/nusl-25823


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Research > Institutes ASCR > Institute of Experimental Medicine
Conference materials > Papers