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Study of plunger pump with linear motor
Machát, Pavel ; Habán, Vladimír (referee) ; Pochylý, František (advisor)
The aim of this thesis is an engineering design of plunger pump with linear motor. This type of pump is used especially for blood pumping in heart surgery. The theoretical part is focused on distribution of pumps, description of extracorporeal circuit and booster heart history. There are basic calculations derived, which describe plunger pump performance. Then varied designs of plunger pumps follows, which are differed in size, shape and application. Next part includes design of reverse valves and their CFD computation.
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Study of plunger pump with linear motor
Jáchym, Jan ; Uttendorfský, Petr (referee) ; Pochylý, František (advisor)
This thesis deals with study and design of plunger pump with linear motor. This pump can be used for blood pumping in heart surgery. The theoretical part of this thesis is focused on description of extracorporeal circuit, heart boosters and artificial heart. This thesis provides an overview of check valves which are used in heart surgery too. Basic equitations for pump design are derived and calculated in this thesis. The pump design and manufacturing by the 3D technology was made by previous results. Finally, in this thesis are compared theoretical results and experimental data.
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Oxygen consumption in awake cardiac surgical patients
Pořízka, Michal ; Stříteský, Martin (advisor) ; Szárszoi, Ondrej (referee) ; Šetina, Marek (referee)
OBJECTIVES: Standard blood flow rates for cardiopulmonary bypass have been assumed to be the same for awake cardiac surgery with thoracic epidural anesthesia as for general anesthesia. However, compared to general anesthesia, awake cardiac surgery with epidural anesthesia may be associated with higher oxygen consumption due to missing effect of general anesthetics. This may result in insufficient oxygen delivery and lactic acidosis when standard blood flow rates were used. The primary aim of our study was to investigate if standard blood flow rates are adequate in awake cardiac surgery. The secondary aim was to evaluate postoperative clinical outcomes of patients undergoing awake cardiac surgery. METHODS: Forty-seven patients undergoing elective on-pump cardiac surgery were assigned to receive either epidural (Group TEA, n=17), combined (Group TEA-GA, n=15) or general (Group GA, n=15) anesthesia. To monitor adequacy of standard blood flow rates, arterial lactate, acid base parameters, central venous and jugular bulb saturation were measured at six time points during in all groups. Blood flow rates were adjusted when needed. Subsequently, early and late postoperative outcome data including hospital and 3-year mortality was recorded and compared among the study groups RESULTS: No lactic acidosis has...
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The effect of hypothermia on outcome and neurologic injury after prolonged cardiac arrest treated by emergency preservation and delayed resuscitation
Drábek, Tomáš ; Jech, Robert (advisor) ; Hess, Ladislav (referee) ; Mareš, Jan (referee)
5 Summary: Currently, the outcomes from traumatic exsanguination cardiac arrest (CA) show that over 50% of deaths due to trauma occur at the scene, where medical care is limited. Less than 10% of patients who become pulseless from trauma survive. However, in an appropriate setting, some of those traumatic injuries could be surgically repairable. Emergency preservation and resuscitation (EPR) is a novel approach for resuscitation of exsanguination CA victims. EPR uses deep hypothermic preservation for prolonged CA to buy time for transport, damage control surgery, and delayed resuscitation with cardiopulmonary bypass (CPB). Initially, we used a dog model to maximize clinical relevance. We showed that the efficacy of EPR is related to the depth of hypothermia and duration of CA. Pharmacologic adjuncts tested to augment hypothermia generally failed. Extended hemorrhagic shock did not prevent the success of EPR vs. conventional resuscitation if extended post-resuscitative hypothermia was provided. Oxygenation of the flush allowed extending of survivable duration of deep hypothermic CA. Because of the lack of molecular tools available for use in dogs, we developed a rat EPR model to study the cellular and molecular mechanisms underlying deep hypothermic neuroprotection to allow us to define specific targets for...
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Oxygen consumption in awake cardiac surgical patients
Pořízka, Michal ; Stříteský, Martin (advisor) ; Szárszoi, Ondrej (referee) ; Šetina, Marek (referee)
OBJECTIVES: Standard blood flow rates for cardiopulmonary bypass have been assumed to be the same for awake cardiac surgery with thoracic epidural anesthesia as for general anesthesia. However, compared to general anesthesia, awake cardiac surgery with epidural anesthesia may be associated with higher oxygen consumption due to missing effect of general anesthetics. This may result in insufficient oxygen delivery and lactic acidosis when standard blood flow rates were used. The primary aim of our study was to investigate if standard blood flow rates are adequate in awake cardiac surgery. The secondary aim was to evaluate postoperative clinical outcomes of patients undergoing awake cardiac surgery. METHODS: Forty-seven patients undergoing elective on-pump cardiac surgery were assigned to receive either epidural (Group TEA, n=17), combined (Group TEA-GA, n=15) or general (Group GA, n=15) anesthesia. To monitor adequacy of standard blood flow rates, arterial lactate, acid base parameters, central venous and jugular bulb saturation were measured at six time points during in all groups. Blood flow rates were adjusted when needed. Subsequently, early and late postoperative outcome data including hospital and 3-year mortality was recorded and compared among the study groups RESULTS: No lactic acidosis has...
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Study of plunger pump with linear motor
Jáchym, Jan ; Uttendorfský, Petr (referee) ; Pochylý, František (advisor)
This thesis deals with study and design of plunger pump with linear motor. This pump can be used for blood pumping in heart surgery. The theoretical part of this thesis is focused on description of extracorporeal circuit, heart boosters and artificial heart. This thesis provides an overview of check valves which are used in heart surgery too. Basic equitations for pump design are derived and calculated in this thesis. The pump design and manufacturing by the 3D technology was made by previous results. Finally, in this thesis are compared theoretical results and experimental data.
|
|
|
Study of plunger pump with linear motor
Machát, Pavel ; Habán, Vladimír (referee) ; Pochylý, František (advisor)
The aim of this thesis is an engineering design of plunger pump with linear motor. This type of pump is used especially for blood pumping in heart surgery. The theoretical part is focused on distribution of pumps, description of extracorporeal circuit and booster heart history. There are basic calculations derived, which describe plunger pump performance. Then varied designs of plunger pumps follows, which are differed in size, shape and application. Next part includes design of reverse valves and their CFD computation.
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