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Bridge on the I/39 road
Pokorná, Šárka ; Svoboda, Adam (referee) ; Panáček, Josef (advisor)
The topic of this Bachelor thesis is design of thle bridge on the I/39 road. Three variants of studies were created. Study C has been choses as the best variant – prefabricated pre-tensioned beams with composite deck. Bridge with one span. Time dependent analysis was taken into account.
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Prestressed road bridge
Pokorná, Šárka ; Jaromír,, Rušar (referee) ; Panáček, Josef (advisor)
The subject of this thesis is the design and assessment of a prestressed bridge structure. Two studies of the bridging were created. The selected variant is a continuous post-tensioned single-frame structure with three spans. The total theoretical span of the bridge is 100,0 m. The bridge is to be constructed in its entirety using a falsework. The structure has been assessed for serviceability limit state and ultimate limit state according to the relevant standards.
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Bridge on the I/39 road
Pokorná, Šárka ; Svoboda, Adam (referee) ; Panáček, Josef (advisor)
The topic of this Bachelor thesis is design of thle bridge on the I/39 road. Three variants of studies were created. Study C has been choses as the best variant – prefabricated pre-tensioned beams with composite deck. Bridge with one span. Time dependent analysis was taken into account.
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Membrane interactions studied by advanced fluorescent techniques: From ions to macromolecules
Pokorná, Šárka ; Hudeček, Jiří (advisor) ; Konopásek, Ivo (referee) ; Benda, Aleš (referee)
Advanced fluorescence techniques were used to explore tree distinct topics concerning biological membrane and their interactions. Following thesis is according to the topic divided into three parts: 1) Ionic effects were studied employing time dependent fluorescence shift experiments and molecular dynamic simulations. Combination of these two approaches are suitable to reveal characteristic like mobility and hydration of particular bilayer segment, lipid packing or ion binding sites. Halide anions were reported to adsorb to the cationic lipid bilayer specifically, altering membrane mobility and organization. Changes in observed parameters follows Hofmeister order. Their effect is mediated either by direct ionic interaction (soft, polarizable ions) as well as via alteration of water structure (hard, non-polarizable ions) in proximity of ion molecule. Further, divalent calcium was shown to bind strongly to neutral and negatively charged lipid bilayers. Several types of binding sites depending on calcium concentration were identified. 2) Two complementary lipopeptides, CPK and CPE, incorporated into distinct lipid bilayers serve as a minimal model inducing membrane fusion. Effectiveness of fusion event might be influenced by lipopeptide-membrane and lipopeptide-lipopeptide interaction. To reveal...
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Drug Addiction and Relations en Famille
POKORNÁ, Šárka
The work deals with the family and drugs. The first part characterises the function and functionless family, her functions and interest to child. Next it describes causes drug addiction, division drugs into legal and illegal, prevention primary, secondary and tertiary. In the practical part there is research drug problem on second school. Most children have experience in drug and reason is within the family.
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