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Perfusion of a Kidney Graft from a Donor After Cardiac Death Based on Immediately Started Pulsatile Machine Perfusion
Opatrný, Václav ; Moláček, Jiří (advisor) ; Bachleda, Petr (referee) ; Havránek, Pavel (referee)
Immediately started pulsatile machine perfusion of a kidney graft from a DCD (donor after cardiac death) as a way to improve its properties Opatrný V. Department of Surgery, University Hospital in Pilsen and Faculty of Medicine in Pilsen, Charles University in Prague Introduction: The number of kidneys available for transplantation still does not match the number of patients on the waiting list, which gets longer every year. At the same time, kidney transplantation is the only chance for the long-term survival of patients with good quality of life. Therefore, organs from marginal donors, including donors after cardiac death (DCD), have recently been used. The most common cause of death of these donors is severe trauma, especially craniocerebral trauma, or sudden cardiac arrest, followed by unsuccessful resuscitation. Kidneys can be harvested once an individual is declared dead according to the exact criteria. This involves initial washing of the grafts in the donor's body using a perfusion solution, followed by their removal and storage using selected preservation method. Mechanical pulsatile perfusion using special instrumentation is the most frequently used technique in the area of DCD. Despite of good long-term outcomes of grafts from DCDs, this group is burdened by a greater number of delayed graft...
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First Year of Donald Trump's Foreign Policy towards DPRK
Opatrný, Václav ; Calda, Miloš (advisor) ; Hornát, Jan (referee)
This Bachelor thesis analyses the main aspects of American foreign policy of Donald Trump's administrative in his first year towards Democratic People's Republic of Korea in context of North Korean nuclear and rocket program. During the year 2017, North Korean regime reached pivotal milestones in nuclear and rocket technologies, which laid the foundations of building large-scale arsenal of intercontinental ballistic missiles with nuclear warheads. This technological progress meant major threat not only for East Asian allies (South Korea and Japan) but even for United States mainland. The policy of previous American administrations did not succeed with solving the North Korean nuclear threat. North Korea proved the capability of circumventing international sanctions and systematically violate agreements. As a result, Donald Trump turned American foreign policy to harder line and primarily used huge American economic and military potential for the enforcement and achievement of his political goals.
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Perfusion of a Kidney Graft from a Donor After Cardiac Death Based on Immediately Started Pulsatile Machine Perfusion
Opatrný, Václav ; Moláček, Jiří (advisor) ; Bachleda, Petr (referee) ; Havránek, Pavel (referee)
Immediately started pulsatile machine perfusion of a kidney graft from a DCD (donor after cardiac death) as a way to improve its properties Opatrný V. Department of Surgery, University Hospital in Pilsen and Faculty of Medicine in Pilsen, Charles University in Prague Introduction: The number of kidneys available for transplantation still does not match the number of patients on the waiting list, which gets longer every year. At the same time, kidney transplantation is the only chance for the long-term survival of patients with good quality of life. Therefore, organs from marginal donors, including donors after cardiac death (DCD), have recently been used. The most common cause of death of these donors is severe trauma, especially craniocerebral trauma, or sudden cardiac arrest, followed by unsuccessful resuscitation. Kidneys can be harvested once an individual is declared dead according to the exact criteria. This involves initial washing of the grafts in the donor's body using a perfusion solution, followed by their removal and storage using selected preservation method. Mechanical pulsatile perfusion using special instrumentation is the most frequently used technique in the area of DCD. Despite of good long-term outcomes of grafts from DCDs, this group is burdened by a greater number of delayed graft...
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