National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Synthesis and structual assignment of novel 5´-epimeric 3´deoxy-3´,4´-didehydronucleoside-5´-C-phosphonates
Petrová, Magdalena ; Buděšínský, Miloš ; Klepetářová, Blanka ; Rosenberg, Ivan
Epimeric 5´-(RS) dialkyl 3-deoxy-3´,4´-didehydro-5´-C-phophonates were prepared by nucleophilic addition of various dialkyl phosphites to 3´-deoxy-3´,4´-didehydronucleoside-5´-aldehydes. Successful separation,crytstallisation and X-ray analysis of a pair of epimeric 5´-C-phosphonates, followed by correlation with a series of NMR parameters, led to efficacious configuration assignment of individual epimers in the mixtures.
Příprava N9-(3-fluoro-2-phosphonomethoxypropyl) (FPMP) derivátů N6-substituovaných adeninů a 2,6-diaminopurinů
Baszczyňski, Ondřej ; Holý, Antonín ; Dračínský, Martin ; Klepetářová, Blanka
An efficient method of the synthesis N9-(3-fluoro-2-phosphonomethoxypropyl) (FPMP) derivatives of purine bases was developed. A series of N6-substituted FPMP dervatives of purine and 2-aminopurine were prepared by using this method.

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