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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
The role of small RNAs in transgenerational plant stress memory
 Jaklová, Veronika ; Marková, Hana (advisor) ; Lipavská, Helena (referee)
Plants are constantly affected by various abiotic and biotic stresses, which cause a whole range of reactions.The resultcanbe increasedplantresistance tovariousstressfactorssuchasherbivoryattack or lack of water. Additionally, this resistance can also be passed on to subsequent generations through epigeneticmechanisms.Small RNAsservingas signaling moleculesof the plant's rapid response tostress can play a large part in the formationof intergenerationalandmultigenerationalstressmemory.MiRNAs are mainly regulators of gene expression,throughtheirinhibitory and degradative activitiesthey control the transcription of genes and the translation of a large number of proteins. SiRNAs could participate in the transfer of transcriptional memory through the mechanism of RNA-directed DNA methylation (RdDM). DNA methylation and histone modifications together act as chromatin marks that can be epigeneticallytransferredtosubsequentgenerations.Basedonthis,plants derivedfromstressedparent plants show large changes in gene expression compared to plants with non-stressed parents. These changesthenpersistfor varyinglengthsof time,dependingon whethergene expressionisagain induced bythe stressfactoror not.Interestinunderstandingthe mechanismsof transgenerationalstressmemory has recently grown considerably, and this...
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A system of a formal assistance to children from children's home in transition to independent life
 Jaklová, Veronika ; Dobiášová, Karolína (advisor) ; Čampulková, Jitka (referee)
This bachelor thesis elaborates preparation of children from children's homes for their independent life as well as subsequent support after their leave from institution, all from perspective of experts. Eventhough problematic of children growing up in institutional care seems to be a relatively often discussed topic, the period of leaving is in practice severely unrecognized by the system. This thesis thus focuses on particular involved actors, their position and role in the system, and on specific areas representing threats while leaving the institution. The issue is viewed from the perspective of bottom-up theory of policy implementation and theory of emerging childhood. Empirical part represents the results of qualitative research, which was conducted with the experts using method of semi-structured interviews.
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