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Tick-borne rickettsial diseases: emerging risks in Europe
Veselá, Petra ; Janovská, Daniela (advisor)
Ricekttsiae are small, gram negative bacteria, known as an etiologic agens of many human as well as animal diseases. The course of rickettsial infections extremely differs in severity. Bacteria are transmitted via arthropodes, infected dust, milk and secretions of infected individuals. Thank to the better hygienical standards many rickettsial infections appear only in the developing countries. On the other hand some other rickettsial infections have higher incidency in atypical countries and ecosystems. This change is thought to be due to global warming. The importance of early diagnosis and proper therapy is common to all infections
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Prognostic indicators of risk of death and the consequences of purulent meningitis
Džupová, Olga ; Janovská, Daniela (advisor) ; Křížová, Pavla (referee) ; Marešová, Vilma (referee) ; Dostál, Václav (referee)
Purulent meningitis is a life-threatening acute infectious disease of the central nervous system. In preantibiotics period was almost one hundred percent fatality rate of disease, with the discovery of antibiotics and their introduction into medical practice in 30th-50th of the last century has decreased dramatically. In recent decades, despite the use of highly effective antibiotics and intensive care procedures, there was no significant reduction in mortality rate and consequences of the disease. Lethal course of the disease affects 15-30% of patients in adulthood. Although not a common infection diagnosis among the top ten infectious causes of death worldwide. The study was based on evaluation of their own group of patients to determine prognostic factors observed history, course of illness and laboratory characteristics of the clinical outcome of disease in adults.
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Haemorrhagic fever and the current situation in the world and in the Czech Republic
El Kurdi, Alexandra ; Janovská, Daniela (advisor) ; Dáňová, Jana (referee)
Viral hemorrhagic fevers are severe diseases caused by specific single stranded, enveloped RNA viruses. These diseases are characteristized by hemorrhages and fever. Vectors are responsible for the transmition of VHFs from rezervoirs to humans. Some of them have existed for over a thousand years while others were recently discovered. They are often found in the tropics or subtropics. VHFs are not endemic to the Czech Republic but there were reports of imported cases of Dengue and hemorrhagic fever with renal syndrome. The objective of my dissertation was literary research of all hemorrhagic fevers and their occurrence. Due to climate change, urbanization, readily available modes of travel and negligence when visiting exotic and endemic regions, VHFs are becoming a global problem. It is extremely important to inform the public on hemorrhagic fevers.
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Epidemiological aspects of Lyme Borreliosis in Czech Republic
Fišerová, Tereza ; Janovská, Daniela (advisor) ; Čelko, Alexander (referee)
The aim of this bachelor work was to collect and to evaluate the data on the incidence of Lyme borreliosis in the Czech Republic in the last ten years (2003-2012). First, a comparison of the incidence of this disease in the administrative regions of the Czech Republic was made, which indicated noticeable differences between the regions. Then, the data for the South Bohemia Region and Vysočina Region were analyzed in a more detail to identify the main factors, which could contribute to the increased incidence of this disease. A brief history of the incidence of Lyme borreliosis worldwide and its etiology is also provided, together with an overview of its clinical manifestations and spread, as well as the corresponding laboratory diagnostic methods and methods of prevention.
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