|
|
Automatic detection of microcalcifications in mammogram images
Hývlová, Denisa ; Jakubíček, Roman (referee) ; Harabiš, Vratislav (advisor)
This bachelor thesis is focused on detection of microcalcification in mammography images. The introduction describes connection between their presence and breast cancer, principle of mammography and the DICOM standard used in radiology. In the following part the methods used for microcalcification enhancement and segmentation are explained. Detection algorithm based on wavelet transform, morphological closing and thresholding was designed in MATLAB. For evaluation of the results a graphical user interface was developed and an algorithm for automatic evaluation of the success rate in annotated mammography database was implemented.
|
|
|
Comparison of Pharmacokinetic Models for Quantification of Blood-Brain-Barrier Opening Induced by Focused Ultrasound
Hývlová, Denisa ; Vitouš, Jiří ; Jiřík, Radovan
This paper focuses on quantification of blood-brainbarrier(BBB) opening induced by focused ultrasound. Dynamiccontrast-enhanced MRI (DCE-MRI) with two different pharmacokineticmodels, 2CX and ETK, is used to evaluate BBB opening.The ETK model is commonly used in BBB-opening studies. Wepropose use of a more advanced model, 2CX, that provides moreaccurate estimation of the BBB permeability. The accuracy of themodels is compared using simulated and real data. The resultsdemonstrate similar performance of the 2CX and ETK models inthe brain region with a highly permeable BBB, but the ETK hasproven unable to correctly detect low level of permeabilization.Thus, the 2CX model is more suitable for the studies of BBBpermeabilitydynamics.
|
|
|
Simulation of Perfusometric Data
Hývlová, Denisa ; Mézl, Martin (referee) ; Jiřík, Radovan (advisor)
This diploma thesis focused on the simulation of perfusion MRI data. The introduction describes standard perfusion imaging methods, DCE and DSC, and the quantitative analysis of perfusion. In the following section, simulation of the perfusion MRI data and the structure of the provided simulation software are described. This software was reworked, and new methods and parameters were implemented. The key product of this work is a simulation study of focused ultrasound-induced blood-brain barrier opening, comparing the pharmacokinetic models used in this application and the accuracy of their permeability estimates. The results of the simulation study were compared with real-dataset results.
|
|
|
Automatic detection of microcalcifications in mammogram images
Hývlová, Denisa ; Jakubíček, Roman (referee) ; Harabiš, Vratislav (advisor)
This bachelor thesis is focused on detection of microcalcification in mammography images. The introduction describes connection between their presence and breast cancer, principle of mammography and the DICOM standard used in radiology. In the following part the methods used for microcalcification enhancement and segmentation are explained. Detection algorithm based on wavelet transform, morphological closing and thresholding was designed in MATLAB. For evaluation of the results a graphical user interface was developed and an algorithm for automatic evaluation of the success rate in annotated mammography database was implemented.
|
guest ::
RSS feed.