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Evaluation of activity of potentional antibacterial substances through the use of microdilution broth method
Andělová, Magdaléna ; Vejsová, Marcela (advisor) ; Jílek, Petr (referee)
Charles University in Prague Faculty of pharmacy in Hradec Králové Department of Biological and Medical science Candidate: Magdaléna And lová Supervisor: Mgr. Marcela Vejsová, Ph.D. Name of diploma thesis: Evaluation of activity of potentional antibacterial substances throught of the use microdilution broth metod Background Aim of this diploma work was research of activity of potentional antimicrobiotic substances. Research of antibacterial substances is one of the most important factor in pharmaceutic industry. The main reason is being the never stopping growth of bacterial resistence. Methods The microdilution broth metod was used to test the substances. This metod was used because of low difficulty and low cost. All the steps including the final analising was done by hand. Results The substances were divided in groups depending their chemical struction. The most effective was the salicylanilide derivates group. The other groups inhibitated growth of bacteria very little or were non-functional. In case of every bacterial stems were analised all substances which were effective. Conclusion Depending on the results the most sensitive and the most resistant bacterial stem were choosen. The most sensitive reaction on tested substances had bacterial stem Staphylococcus aureus. The Klebsiella pneumoniae...
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"The experience of alcohol-addicted clients after institutional treatment"
Andělová, Magdalena ; Libra, Jiří (advisor) ; Vacek, Jaroslav (referee)
Bases: In institutional care, the clients are taken out of their natural ambient. In safe institutional ambience, the abstinence is easier. During the institutional treatment, the client should get new overview of his addiction, enforce his decision for a change and reevaluate his lifestyle. The clients often return back to their unsatisfying living conditions. The addiction influences all domains of human existence, therefore it is important that clients get the care in accordance with their needs during and after the institutional treatment. Aims: The main aim of this thesis is to find how the alcohol addicted clients, the clients repetitively hospitalized for the relapses, lived through the retrieve into the normal life after the institutional treatment. The other aim is to find usual problems that arise after the treatment and reasons for the relapse. Moreover, the question is what the experience with the aftercare care is and what is the main support on their way to recovery. I have focused on the period between the first and the last treatment. The principal research questions: Which factors influenced the relapse of the clients? Other research questions: What are the experiences with the aftercare programs? Which factors do the clients feel as supporting on their way to recovery?...
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"The experience of alcohol-addicted clients after institutional treatment"
Andělová, Magdalena ; Libra, Jiří (advisor) ; Vacek, Jaroslav (referee)
Bases: In institutional care, the clients are taken out of their natural ambient. In safe institutional ambience, the abstinence is easier. During the institutional treatment, the client should get new overview of his addiction, enforce his decision for a change and reevaluate his lifestyle. The clients often return back to their unsatisfying living conditions. The addiction influences all domains of human existence, therefore it is important that clients get the care in accordance with their needs during and after the institutional treatment. Aims: The main aim of this thesis is to find how the alcohol addicted clients, the clients repetitively hospitalized for the relapses, lived through the retrieve into the normal life after the institutional treatment. The other aim is to find usual problems that arise after the treatment and reasons for the relapse. Moreover, the question is what the experience with the aftercare care is and what is the main support on their way to recovery. I have focused on the period between the first and the last treatment. The principal research questions: Which factors influenced the relapse of the clients? Other research questions: What are the experiences with the aftercare programs? Which factors do the clients feel as supporting on their way to recovery?...
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Evaluation of activity of potentional antibacterial substances through the use of microdilution broth method
Andělová, Magdaléna ; Vejsová, Marcela (advisor) ; Jílek, Petr (referee)
Charles University in Prague Faculty of pharmacy in Hradec Králové Department of Biological and Medical science Candidate: Magdaléna And lová Supervisor: Mgr. Marcela Vejsová, Ph.D. Name of diploma thesis: Evaluation of activity of potentional antibacterial substances throught of the use microdilution broth metod Background Aim of this diploma work was research of activity of potentional antimicrobiotic substances. Research of antibacterial substances is one of the most important factor in pharmaceutic industry. The main reason is being the never stopping growth of bacterial resistence. Methods The microdilution broth metod was used to test the substances. This metod was used because of low difficulty and low cost. All the steps including the final analising was done by hand. Results The substances were divided in groups depending their chemical struction. The most effective was the salicylanilide derivates group. The other groups inhibitated growth of bacteria very little or were non-functional. In case of every bacterial stems were analised all substances which were effective. Conclusion Depending on the results the most sensitive and the most resistant bacterial stem were choosen. The most sensitive reaction on tested substances had bacterial stem Staphylococcus aureus. The Klebsiella pneumoniae...
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