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Technology of production vertical wiring duct for low-voltage switchgear ABB
Šín, Martin ; Peterková, Eva (referee) ; Dvořák, Milan (advisor)
The bachelor thesis presents the design of the technology for production of a vertical cable tray for ABB low voltage switchboards. The assembly consists of two parts. Cable gutter and shielding partition are made of galvanized sheet 11 321, quality DX52D+Z275MB with material thickness 1 mm. Manufacturing of the component by means of punching, laser cutting, bending on the bending press and joining of individual parts using the clinching method was designed based on the study and calculations. Everything is documented by calculation and drawing documentation.
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Micropulse Laser Therapy of Cystoid Macular Edema
Závorková, Martina ; Jirásková, Naďa (advisor) ; Chrapek, Oldřich (referee) ; Šín, Martin (referee)
Micropulse laser therapy of cystoid macular edema Introduction: Diabetic retinopathy (DR) is a typical microvascular complication of diabetes mellitus (DM). The most common manifestation of DR that reduces vision is diabetic macular edema (DME). The objective of this study was to evaluate the efficacy of DME therapy using subthreshold micropulse laser (SMPL) with a wavelength of 577 nm. Cohort and methods: The cohort with a monitoring period of 1 year included the total number of 167 eyes of 111 patients with DME. The cohort with a monitoring period of 3 years included the total number of 70 eyes of 47 patients. The cohort with a monitoring period of 5 years included the total number of 52 eyes of 34 patients. None of the patients met the reimbursement criteria for DME treatment with intravitreal administration of anti-VEGF or did not wish to undergo that treatment. All the eyes underwent treatment of the retina outside the macula with a standard laser pulse therapy. The treatment depended on the type of DR. On the day of being included in the study, DME therapy using SMPL. Subsequent check-ups were followed every 3 months in the first year of the treatment, and every 4 to 6 months in the following years. The laser treatment of the retina was repeated during the check-ups as needed. The treatment...
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The evaluation of the effect in supression of the inflammatory reaction by oral intake Relifex (nabumeton) after photodynamic therapy in the treatment of exsudative age-related macular degeneration
Šín, Martin ; Jirásková, Naďa (advisor) ; Sosna, Tomáš (referee) ; Dotřelová, Dagmar (referee)
Purpose: To evaluate photodynamic therapy (PDT) combined with the preferential the cyclooxygenase-2 (COX-2) inhibitor, nabumetone in the treatment of the neovascular age-related macular degeneration (ARMD). Methods: A prospective, double-blind, randomized study on 60 patients with subfoveal CNV secondary to ARMD without any previous treatment. Patients were divided into a nabumetone or placebo group. The main endpoints were the change of best-corrected visual acuity (BCVA), central macular thickness (CRT) and number of required PDT treatments Results: In the nabumetone group, 27 patients (90%) and 28 (93%) in the placebo group completed the follow-up of 12 months. In the nabumetone group, the mean CRT decreased from 332 μm (SD 68 μm) to 220 μm (SD 46 μm). In the placebo group, CRT decreased from 331 μm (SD 72 μm) to 254 μm (SD 61 μm). The mean BCVA was 0.68 log MAR (SD 0.22 log MAR) in the nabumetone group and 0.62 log MAR (SD 0.23 log MAR) in the placebo group at baseline. This stabilised in the placebo group to 0.66 log MAR (SD 0.33) but deteriorated in the nabumetone group to 0.86 logMAR (SD 0.41 logMAR). There was a significant reduction in the number of required PDTs in the nabumetone group, but significant progression of the RPE atrophy area. Conclusion: Combined PDT with oral intake of the COX-2...
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Surgical Treatement of Idiopathic Macular Hole Using Different Types of Tamponades and Different Postoperative Positioning Regimen
Veith, Miroslav ; Studnička, Jan (advisor) ; Šín, Martin (referee) ; Chrapek, Oldřich (referee)
Surgical treatement of idiopathic macular hole using different types of tamponades and different postoperative positioning regimen Summary Aim: To compare the effect of different types of intraocular tamponade and different types of postoperative positioning on the closure of an idiopathic macular hole (IMH). Design: Prospective randomized clinical trial. Methods: In this work we evaluate the surgical results of 104 eyes of 100 patients (76 women, 24 men) who were operated for IMH. The mean age of the patients was 70,8 years (57 - 87). The mean initial best corrected visaul acuity (BCVA) was 0,15 (0,05 - 0,50). The mean extend of the macular hole at the narrowest point was 408,5 µm (133 - 741). All patients were operated using a 25-gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling under retrobulbar anesthesia. Patients were randomized into the following four groups: SF6 + reading position (n = 26), air + reading position (n = 25), air + prone position (n = 26) or SF6 + prone position (n = 27). Results: The follow-up period is 6 months. Closure rate of all IMD was 83,7 % (In the 1st group 100 %, in the 2nd 56 %, in the 3rd 84,6 % and in the 4th group 92,6 %). The air tamponade + reading position group was statistically significantly less successful compared to the other three...
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Technology of production vertical wiring duct for low-voltage switchgear ABB
Šín, Martin ; Peterková, Eva (referee) ; Dvořák, Milan (advisor)
The bachelor thesis presents the design of the technology for production of a vertical cable tray for ABB low voltage switchboards. The assembly consists of two parts. Cable gutter and shielding partition are made of galvanized sheet 11 321, quality DX52D+Z275MB with material thickness 1 mm. Manufacturing of the component by means of punching, laser cutting, bending on the bending press and joining of individual parts using the clinching method was designed based on the study and calculations. Everything is documented by calculation and drawing documentation.
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The evaluation of the effect in supression of the inflammatory reaction by oral intake Relifex (nabumeton) after photodynamic therapy in the treatment of exsudative age-related macular degeneration
Šín, Martin ; Jirásková, Naďa (advisor) ; Sosna, Tomáš (referee) ; Dotřelová, Dagmar (referee)
Purpose: To evaluate photodynamic therapy (PDT) combined with the preferential the cyclooxygenase-2 (COX-2) inhibitor, nabumetone in the treatment of the neovascular age-related macular degeneration (ARMD). Methods: A prospective, double-blind, randomized study on 60 patients with subfoveal CNV secondary to ARMD without any previous treatment. Patients were divided into a nabumetone or placebo group. The main endpoints were the change of best-corrected visual acuity (BCVA), central macular thickness (CRT) and number of required PDT treatments Results: In the nabumetone group, 27 patients (90%) and 28 (93%) in the placebo group completed the follow-up of 12 months. In the nabumetone group, the mean CRT decreased from 332 μm (SD 68 μm) to 220 μm (SD 46 μm). In the placebo group, CRT decreased from 331 μm (SD 72 μm) to 254 μm (SD 61 μm). The mean BCVA was 0.68 log MAR (SD 0.22 log MAR) in the nabumetone group and 0.62 log MAR (SD 0.23 log MAR) in the placebo group at baseline. This stabilised in the placebo group to 0.66 log MAR (SD 0.33) but deteriorated in the nabumetone group to 0.86 logMAR (SD 0.41 logMAR). There was a significant reduction in the number of required PDTs in the nabumetone group, but significant progression of the RPE atrophy area. Conclusion: Combined PDT with oral intake of the COX-2...
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