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Nursing care of child patient with acute pancreatitis.
ŽENÍŠKOVÁ, Pavla
Abstract Child patient acute pancreatitis nursing care Current status: Acute pancreatitis is an inflammatory disease of the pancreas. This disease can be classified as an acute abdominal event. The essence of the disease is the autodigestion of pancreas maternal tissues. The most common cause of pancreatitis in childhood is an infection. This infection may have viral, bacterial or parasitary origin. The main clinical symptom is abdominal pain, connected with vomiting. The diagnosis can be confirmed by a laboratory blood test, where increased values of amylase and lipase are found in the serum. For acute pancreatitis diagnosis in pediatric patients, a non invasive displaying method has remained unsurpassed up to now - ultrasonographic abdominal examination. The method is non-invasive, Quit and available examination. Based on the progression and form of the disease, the child patient is admitted to an intensive care unit, or to a standard ward. The onset of treatment requires the absolute prohibition of any intake of nutrition per os. The application of analgetics and antibiotics is also very important. Regarding the application of analgetics there are different opinions regarding opiate or non-opiate types., Some complications can occur in more serious forms of the disease, like biliar ways compression followed by icter, duodena stenosis and following ileus. There are also connected complications regarding the cardio vascular system and the gastroinstestinal tract. The prognosis is very good in milder forms of the disease. Acute pancreatitis can turn into the chronic disease in 15-35% of cases. Targets: The first target was to evaluate the acute pancreatitis growth rate in childhood in the Czech republic from 2004 up to 2014. The second target was to describe specific aspects of nursing care for the pediatric patient with acute pancreatitis during hospitalization, during follow up care and after being released home. Methodology and research group: The Institute of sanitary information and statistics was appproached regarding the achievment of the first tagret as were all seven health insurance companies operating in the Czech republic. The method of documents analysis and data collection was used to achieve the second target. The information was gathered from primary documentation and professional studies on the topic. Results: From 2010 there has been a constant and gradual growth of acute pancreatitis in pediatric patients in the Czech republic. While in 2010 there were 221 patients, in 2014 there were already 318 pediatric patients with this disease. The specific aspects of nursing care for a pediatric patient with acute pancreatitis are in early diagnostics, analgetics and antibiotics therapy, and mainly, in dietary measures. During hospitalization in an intensive care unit, or in a standard ward, the specific aspects of nursing care are the following: Physiological functions monitoring, pain monitoring, monitoring the intravenous catheter, or urine catheter if applicable, and nazogastric probe, observing the emptying and nutrition of a pediatric patient, and also in meeting the child´s needs. The most important aim after acute pancreatitis, is maintaining the correct diet. The gradual return of the child back to normal life is also very important. Conclusion: This disease can be classified as an acute abdominal event. The clinical image is accompanied by strong abdominal pain and vomiting. Ultrasonogprahic abdominal examination is the first option of displaying diagnostic methods. The treatment takes place during hospitalization in an intensive care unit or in a standard ward. Strict diet maintaining is the most important specific aspect. Practical recommendations: The outcome of the thesis is a brief summary of nursing care for a child with a past of acute pancreatitis when is discharged home.
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Test of medicaments perspective for exploitment at the fishing profession
SCHEINER, Pavel
The aim of the study was to assess the effects of orally applied praziquantel on the treatment efficacy against most abundant tapeworms (Atractolytocestus huronensis Anthony, 1958 and Khawia sinensis Hsü, 1935) of common carp (Cyprinus carpio Linnaeus). Naturally infected fish (one-year-old; K1+) were divided into 3 trial groups containing 17 specimens and administered with praziquantel mixed in heat-treated amyloid vehicle (in doses of 50 mg.kg-1 body weight). In 3 groups of control, the fish were administered amyloid vehicle only. Fish were examined by using of gut dissection 2, 4 and 6 days after administration. At 48 hours post-treatment, significantly lower prevalence of both parasites was found. The invasion of A.huronensis was fully eliminated in all fish after 96 hours whereas some specimens of K.sinensis still persisted in the gut of few fish. The full elimination of both parasites was observed 6 days after administration. Our results showed that elimination of K. sinensis takes longer than elimination of A.huronensis. The dose of 50 mg kg-1 of orally applied praziquantel is effectual to control A.huronensis and K sinensis infections in common carp successfully. The effect of oral applied praziquantel on the hematology and biochemical parameters blood of common carp (Cyprinus carpio L.), infected by the tapeworms Atractolytocestus huronensis and Khawia sinensis was the object of analyse. It was the partial goal of the work. The infected fishes were divided to the six groups. The praziquantel was applied stirred in amyloid vehicle in dose 30 mg/kg of quick materiality for two groups and for two to other groups in dose 50mg/kg of quick materiality. Only clean amyloid vehiculum was applied to two control groups. Blood taking and resulting patoanatomic investigation was effected 24 and 96 hours after application of praziquantel. Results of hematology investigation of blood obtained 24 hours after the application point on significant fall (p< 0,01) of the number of erythrocytes, hemoglobin and hematocrit in both groups E1 and E3, which achieved the original surface after 96 hours. The significant upsurge (p<0,05) of the surface serum hepatic enzyme ALT was recorded after 96 hours.
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Prevention of Cervical Cancer
Kafková, Simona ; Šafář, Petr (advisor)
Cervical cancer is a disease characterized by an abnormal growth of cells in the uterine cervix. It is caused by an infection with a range of high risk oncogenic human papillomavirus (HPV) and it is now accepted that more that 99 % of the cervical cancer is initiated by the HPV infection. HPV is the most common sexually transmitted viral disease. Most of the HPV infections are only temporary and human organism can destroy the infection with its own immune response. A persistent infection can lead to the malign transformation and an uncontrolled cell proliferation. There are more than 10 years between an epithelial infection and cervical cancer. Prevention of cervical cancer includes an HPV protection, an early diagnosis and a treatment. In spite of the fact that there has been enormous progress in the area of the cervical cancer prevention when vaccination against the most common HPV types was discovered, an early precancerous diagnosis through the use of the full-area screening still remains an essential precaution. The screening still needs to be provided not only to unvaccinated women but also to the immunized ones because current vaccines protect only against 80% of the oncogenic HPV types. Because of the prolonged absence of clinical symptoms in precancerous stages, the cytodiagnosis is the only method...
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Cryptosporidial infections of pigs
FORNBAUMOVÁ, Iva
Recent genetic and biological characterization studies have identified 2 distinct apparently host-adapted genotypes of Cryptosporidium in pigs, that is, Cryptosporidium suis and the Cryptosporidium pig genotype II. The infection of both the above mentioned Cryptosporidium appears to occur a much less severe disease in pigs than it does Cryptosporidium parvum. Sporadic cases of C. suis in human have been reported, but the risk of infection for human is uncertain.
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Zdravotní stav lipové aleje na Masarykově třídě v Liberci
Knoppová, Michaela
The goal of this work is to evaluate and document the health status of the Masaryk alley in Liberec. The health of the alley was negatively affected by the reconstruction of the whole street due to the expansion of the tram tracks and replacement of the underground utilities network. During those works the root system of the trees was significantly damaged, allowing for easier infection by the wood-decay fungi like the Ustulina deusta a Pholiota squarosa. Further spread of those dangerous wood-decay fungi can be contributed to the very frequent tears and other mechanical damage.
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Cryptosporidial and microsporidial infection on the pig farms, in the Czech Republic
HANZLÍKOVÁ, Dagmar
The cryptosporidia and microsporidia are worldwide spread opportunistic parasites. With regard to their wide host spectra and zoonotic potential there is a significant risk for immunocompromised humans, especially AIDS patients. Natural Cryptosporidium infections in pigs are widespread but generally apathogenic. A total of 411 faecal samples, 39 of sows, 127 of pre-weaned, 122 of post-weaned piglets and 123 of pre-growers from three farms were screened for Cryptosporidium spp. infection using the aniline-carbol-methyl violet staining method and positive molecular characterized (direct sequencing of partial SSU rRNA partial genes and PCR-RFLP at the SSU rRNA). Overall, infections were detected in 84 out of 411 animals (20 %), with highest infection rates among post-weaners (27 %). All positive samples were genotyped based on SSU rRNA sequence analysis. C. suis, Cryptosporidium pig genotype II, and C. muris were detected. The microsporidial infections are very frequent in breeds of pigs. Pigs have been frequently reported to be infected with E. bieneusi. Spores were detected in 258 samples of 342 (75 %). The high prevalence was determined in pre-growers (86 %). Genotyping based on the ITS regions of the rRNA gene identified that most pigs were infected with the species-specific genotype F, while two animals had the zoonotic genotype D and two had genotype Peru 9.
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Cytomegalovirus infection after kidney transplantation
Reischig, Tomáš ; Třeška, Vladislav (advisor) ; Viklický, Ondřej (referee) ; Zadražil, Josef (referee) ; Pazdiora, Petr (referee)
1 SUMMARY Cytomegalovirus (CMV) disease is a common infectious complication in patients after solid organ transplantation. The last decade witnessed major advances in CMV disease prevention. Use of universal prophylaxis or preemptive therapy resulted in a decrease in the incidence of CMV disease from 20-60% to 5-20%. However, the efficacy of preventive approaches in terms of indirect effects of CMV occurrence is problematic. Association with allograft rejection belongs to well documented and clinically extremely important indirect effects of CMV with a prolonged adverse impact on graft survival. Potential mechanisms include overexpression of major histocompatibility complex molecules, growth factors and cytokines, and upregulation of adhesion molecules. A number of questions remain to be answered in evaluating CMV as a risk factor for acute rejection. While CMV disease is associated with an increased incidence of acute rejection, data regarding the role of asymptomatic CMV viremia are controversial. In our research we evaluated the role of CMV in pathogenesis of allograft rejection in the era of modern immunosuppression and CMV prophylaxis as well as optimal preventive strategy to minimize impact of CMV. In the first trial, renal transplant (RTx) recipients were followed prospectively for 12 months to...
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Autoimmune thyroiditis in children and the role of simultaneous Helicobacter pylori infection
Pomahačová, Renata ; Sýkora, Josef (advisor) ; Hníková, Olga (referee) ; Kalvachová, Božena (referee)
1. Summary The first aim of our study was to find out the present occurence of H. pylori infection in a group of children with juvenile lymphocytic thyroiditis (JLT) and to compare with the prevalence of this infection in a group of healthy children of the same age. The group of patients with JLT included 199 children (range 0-18 years). H. pylori infection was confirmed in 15 patients (7,5%) by a non-invasive diagnostic test of H. pylori antigen positivity in stools by the ELISA test using monoclonal antibodies (Amplified IDEIQA HpStAR ELISA, DakoCytomation, Glostrup, Denmark). This H.pylori positive group included 14 girls and 1 boy aged 11,2 ±2,3. 6 children had hypofunction of the thyroid gland, in 3 children was established the atrophic form of the thyroiditis with severe hypothyroidism with presence of myxoedema, the other children suffered from the hypertrophic form of the thyroiditis. 7 subjects underwent gastroscopy which confirmed chronic active gastritis. Only 3 children had gastrointestinal symptoms caused by H. pylori infection, the other children were asymptomatic. This finding confirms common information about asymptomatic development of H. pylori infection in children in 90% of cases. The control group included 1545 asymptomatic healthy children in range of 0-15 years of the same geographic...
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