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National Repository of Grey Literature 3 records found  Search took 0.01 seconds. 
Importance of particular regions of CNS in the development of opioid addiction
 Vyvadilová, Tereza ; Hejnová, Lucie (advisor) ; Roubalová, Lenka (referee)
Opiods are used as the most powerful painkillers in the medicine. The mechanism of their effect is determined by binding to the opioids receptors located in the central nervous system and peripheral nervous system. The opioids have high potential to develop addiction. Significance of psychical addiction belongs to losing control above using and compulsive desire to obtain drug of abuse to achieve certain psychical state. The somatic part is increase tolerance demonstrating need of dose increasing to achieve required effect. This thesis summarizes knowledge about particular regions of the central nervous system which participate on developing of addiction as ventral tegmental area, nucleus accumbens, locus coeruleus, ventral pallidum and amygdala. It seems that main role in developing of addiction acts the mesolimbic reward system which relates with increased release of dopamine resulting in stimulation of the brain reward system.
Detailed record
The role of the brain in the formation of a specific psychopathology of anorexia nervosa
 Tomášová, Kateřina ; Daňková, Pavlína (advisor) ; Čerešňáková, Silvie (referee)
Detailed record
Importance of particular regions of CNS in the development of opioid addiction
 Vyvadilová, Tereza ; Hejnová, Lucie (advisor) ; Roubalová, Lenka (referee)
Opiods are used as the most powerful painkillers in the medicine. The mechanism of their effect is determined by binding to the opioids receptors located in the central nervous system and peripheral nervous system. The opioids have high potential to develop addiction. Significance of psychical addiction belongs to losing control above using and compulsive desire to obtain drug of abuse to achieve certain psychical state. The somatic part is increase tolerance demonstrating need of dose increasing to achieve required effect. This thesis summarizes knowledge about particular regions of the central nervous system which participate on developing of addiction as ventral tegmental area, nucleus accumbens, locus coeruleus, ventral pallidum and amygdala. It seems that main role in developing of addiction acts the mesolimbic reward system which relates with increased release of dopamine resulting in stimulation of the brain reward system.
Detailed record

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