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Adherence to pharmacotherapy of osteoporosis
Santariová, Martina ; Vytřísalová, Magda (advisor) ; Doseděl, Martin (referee)
ADHERENCE TO PHARMACOTHERAPY OF OSTEOPOROSIS Author: Martina Santariová Supervisor: PharmDr. Magda Vytřísalová, Ph.D. Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy INTRODUCTION: Adherence is the extent to which the patient's behavior (using of medication, following recommended regimen) is in accordance with the advice of the health care provider. Adherence to pharmacotherapy of osteoporosis, including compliance and persistence, is still suboptimal. OBJECTIVE: The objective of the study was assessing of subjectively evaluated adherence with peroral bisphosphonates used to treat osteoporosis within Czech women. METHODS: A cross-sectional multicentre survey. Data collecting was carried out using anonymous questionnaire in five osteocenters in the Czech Republic. The research was performed between November 2012 and March 2013. Adherence was evaluated using a standardized questionnaire OS- MMAS (Osteoporosis-specific Morisky Medication Adherence Scale). RESULTS: A total of 363 postmenopausal women aged 55 years and older with osteoporosis or osteopenia were participated in the study. 133 (36,6 %) women used weekly dosage forms of BIS (alendronate, alendronate and vitamine D in a fixed combination, risedronate) and 230 (63,4 %) women used...
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The relation of odor exposure, olfactory abilities, and odour awareness for six year olds children.
Vojtušová Mrzílková, Radka ; Martinec Nováková, Lenka (advisor) ; Třebická Fialová, Jitka (referee)
A great degree of interindividual variability has been established in measures of psychophysical olfactory performance and odor awareness in both children and adults. Previous studies have suggested the possibility that one of the factors that might contribute to this variability might be the degree of odor exposure in everyday contexts. In the present study, we hypothesized that children exposed to a greater variety of odors on a more frequent basis would exhibit higher odor identification and odor awareness scores. We have found an effect of odor exposure on the children's olfactory knowledge as reflected in their reports of olfactory behavior, but not olfactory abilities. In so doing, we replicated some of the previous findings in the literature of female over male advantage in the olfactory domain. Namely, we report that girls showed a more profound understanding of their olfactory environment and a greater degree of olfaction-oriented behavior, which was not accounted for by a gender difference in verbal fluency. Nevertheless, girls did not outperform boys on either of the measures of olfactory performance. Semi-longitudinal and longitudinal studies in verbally proficient children, employing both self- and parental reports of children's odor exposure and repeated olfactory testing, might...
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Adherence to pharmacotherapy of osteoporosis
Santariová, Martina ; Vytřísalová, Magda (advisor) ; Doseděl, Martin (referee)
ADHERENCE TO PHARMACOTHERAPY OF OSTEOPOROSIS Author: Martina Santariová Supervisor: PharmDr. Magda Vytřísalová, Ph.D. Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy INTRODUCTION: Adherence is the extent to which the patient's behavior (using of medication, following recommended regimen) is in accordance with the advice of the health care provider. Adherence to pharmacotherapy of osteoporosis, including compliance and persistence, is still suboptimal. OBJECTIVE: The objective of the study was assessing of subjectively evaluated adherence with peroral bisphosphonates used to treat osteoporosis within Czech women. METHODS: A cross-sectional multicentre survey. Data collecting was carried out using anonymous questionnaire in five osteocenters in the Czech Republic. The research was performed between November 2012 and March 2013. Adherence was evaluated using a standardized questionnaire OS- MMAS (Osteoporosis-specific Morisky Medication Adherence Scale). RESULTS: A total of 363 postmenopausal women aged 55 years and older with osteoporosis or osteopenia were participated in the study. 133 (36,6 %) women used weekly dosage forms of BIS (alendronate, alendronate and vitamine D in a fixed combination, risedronate) and 230 (63,4 %) women used...
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