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Optic disc segmentation in retinal images
Vymazal, Bronislav ; Odstrčilík, Jan (referee) ; Kolář, Radim (advisor)
Cílem této práce bylo vytvořit kompaktní algoritmus sloužící k lokalizaci, segmentaci a sledování optického disku v sekvencích obrazů sítnice. Pro účely lokalizace byla použita nová metoda založena na „fast radial transform“. Segmentace optického disku je založena na klasické metodě Chan-Vese, která byla rozšířena o další prvky a implementována v lokalizované podobě, která umožňuje lépe segmentovat obrazy s vysokou mírou nehomogenity. Pro sledování optického disku v sekvencích obrazů byl využit optický tok založený na Lucas-Kanade algoritmu. Všechny metody byly vyhodnoceny na dvou databázích obrazů s odlišnými charakteristikami. První databází je klasická databáze s vysokým rozlišením. Druhou je pak databáze s nízkým rozlišením a vysokou mírou šumu. Všechny výsledky jsou pak porovnány s referenčními hodnotami a vyhodnoceny.
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Detection of blood-vessel bifurcations in retina
Baše, Michal ; Zoltán, Szabó (referee) ; Kolář, Radim (advisor)
This master thesis deals with detection of blood-vessel bifurcations in retinal images and its properties. There are explained procedure of taking photographs of retina by fundus camera, optical coherence tomography (OCT) and scanning laser opthalmoscope (SLO) and properties of fundus images are described. In this thesis are mentioned some effective thresholding methods and there are explained the most important morphological operations with binary images, as well as with grayscale images. Detected bifurcations are used for image registration with second-order polynomial transformation using corresponding bifurcations.
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Multimodal retinal image registration
Štohanzlová, Petra ; CSc, Tomáš Suk, (referee) ; Harabiš, Vratislav (advisor)
This work deals with possibilities of registration of retinal images from different mo-dalities, concretely optical coherence tomography (OCT), scanning laser ophthalmoscopy (SLO) and fundus camera. In first stage is the interest focused on registration of SLO and fundus images, which will serve to determine area of interest for consecutive registration of OCT data. The final stage is finding correct location of OCT B-scans in fundus image. On the basis of the studied methods of registration was chosen method making use of computation of correlation coefficient for both cases. For finding optimal parameters of registration is used searching through whole space of parameters. In partial stages of the work was created algorithm for alignment of B-scans followed by detection of blood vessels and also simple algorithm for detection of blood vessels from fundus image. For more transparent registration the graphical user interface was created, which allows loading input images and displaying the result in several possible forms.
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Retinal image registration using phase correlation
Šikula, Viktor ; Harabiš, Vratislav (referee) ; Kolář, Radim (advisor)
This master thesis deals with retinal image registration using phase correlation technique. There are described properties of retinal images and modality of scanning. A geometrical transformation encompasing scale, rotation and translation between two retinal images is considered and the whole registration framework is described. There are used retinal images from fundus camera and scanning laser ophthalmoscope (SLO). In this thesis is described corresponding bifurcations detection using phase correlation and registration using second-order polynomial transformation. The results are subjectively and objectively verificated.
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Software for retinal image processing
Magula, Filip ; Fiala, Jiří (referee) ; Kolář, Radim (advisor)
This thesis deals with practical solutions of software for retinal images digital processing. The theoretic part describes human eye and retinal anatomy and also glaucoma disease. It is also focused on description of method for retinal nerve fiber layer enhancement and analysis. These enhancement are then used for designing of automated image processing. One chapter is devoted to detection and analysis of retinal nerve fibers layer. The practical part includes the user manual for application Image Blockz, which was established within this thesis. Further practical part contains the programmer's manual describing the basic structure of the program and its possible extensions.
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Texture analysis of retinal images
Mikauš, Jakub ; Odstrčilík, Jan (referee) ; Gazárek, Jiří (advisor)
The thesis deals with the detection of the nerve fiber layer disruptions in retina scans. The introduction presents an overview of the human eye fysiology and analyses the input image data. The thesis continues with an investigation of two texture analysis methods. While the method of adapted filters does not produce very good results, the method of brightness assessment is shown to work satisfactorily. The final part of the thesis describes the implemented tool for the detection of the nerve fiber layer disruptions.
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A Classification Methods for Retinal Nerve Fibre Layer Analysis
Zapletal, Petr ; Kolář, Radim (referee) ; Odstrčilík, Jan (advisor)
This thesis is deal with classification for retinal nerve fibre layer. Texture features from six texture analysis methods are used for classification. All methods calculate feature vector from inputs images. This feature vector is characterized for every cluster (class). Classification is realized by three supervised learning algorithms and one unsupervised learning algorithm. The first testing algorithm is called Ho-Kashyap. The next is Bayess classifier NDDF (Normal Density Discriminant Function). The third is the Nearest Neighbor algorithm k-NN and the last tested classifier is algorithm K-means, which belongs to clustering. For better compactness of this thesis, three methods for selection of training patterns in supervised learning algorithms are implemented. The methods are based on Repeated Random Subsampling Cross Validation, K-Fold Cross Validation and Leave One Out Cross Validation algorithms. All algorithms are quantitatively compared in the sense of classication error evaluation.
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Detection of the retinal nerve fibre layer
Kunc, Martin ; Szabó, Zoltán (referee) ; Kolář, Radim (advisor)
This thesis is deals with the nerve fibre layer in the colour ophthalmology images of retina. The thesis describes how can we use finding of nerve fibre layer and how was it solved in the past. In the thesis are proposed the methods that are based on processing and scoring frequency spectrums of individual sample of retina. At first here are described the methods of detection on the artificial generated samples that just simulate the nerve fibre layer. Then the thesis concentrates on processing of real images of retina. Because of the bloodstream, that depreciates processing at real images, are all surveyed samples are chosen manually. Except detection the nerve fibre layer itself, the thesis also deals with determination of direction their dissemination.
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Function of retina of Homing pigeon \kur{Columba livia} in magnetoreception
BAJGAR, Adam
Many animals have ability to percieve the magnetic field of the Earth and use this clue for both orientation and navigation. Yet little is known about physiological mechanism that underlies this sensory ability. Although physiological mechanism still remains unclear, there are three major hypotheses how animals can detect the magnetic field. In this study I focused on the radical pair theory. I analyzed how manipulation of the ambient magnetic field influence the expression of CRY 1, CRY 2 and c-Fos in the pigeon´s retina. I observed in incerased numbers of CRY1, c-Fos and CRY1+c-Fos possitive cells in the ihned nuclear layer (INL) of the retina in animals sbjected to the periodical manipulation of the magnetic field inclination. These data demonstrate that the INL constains a population of neurons that are responsive to magnetic stimuli and strongly suggest that Cry 1 is involved in detection of the Earth magnetic field.
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