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Impact of glucocorticoid treatment on musculosceletal system of pediatric patients with acute lymphoblastic leukemia.
Petráčková, Karolína ; Jevič, Filip (advisor) ; Šrámková, Lucie (referee)
This bachelor thesis aims to provide a general overview of complications of musculoskeletal system in pediatric patients diagnosed with acute lymphoblastic leukemia (ALL) undergoing chemotherapy treatment involving high cumulative doses of glucocorticoids. Musculoskeletal complications include steroid myopathy, osteonecrosis and reduced bone mineral density. The first part describes their basic pathophysiological mechanisms and the risk factors of their origin. The second part presents the current possibilities of muscle strength assessment and available exercise programs. Furthermore, diagnosis of osteonecrosis and bone mineral density are presented together with current possibilities of therapeutic intervention. The thesis also covers characteristics of muscle strength measuring methods and exercise programs along with presentation of the results of individual studies. In the discussion part, there are broken down the limits, advantages and disadvantages of using the muscle strength measuring methods and exercise programs in clinical practice.
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Impact of glucocorticoid treatment on musculosceletal system of pediatric patients with acute lymphoblastic leukemia.
Petráčková, Karolína ; Jevič, Filip (advisor) ; Šrámková, Lucie (referee)
This bachelor thesis aims to provide a general overview of complications of musculoskeletal system in pediatric patients diagnosed with acute lymphoblastic leukemia (ALL) undergoing chemotherapy treatment involving high cumulative doses of glucocorticoids. Musculoskeletal complications include steroid myopathy, osteonecrosis and reduced bone mineral density. The first part describes their basic pathophysiological mechanisms and the risk factors of their origin. The second part presents the current possibilities of muscle strength assessment and available exercise programs. Furthermore, diagnosis of osteonecrosis and bone mineral density are presented together with current possibilities of therapeutic intervention. The thesis also covers characteristics of muscle strength measuring methods and exercise programs along with presentation of the results of individual studies. In the discussion part, there are broken down the limits, advantages and disadvantages of using the muscle strength measuring methods and exercise programs in clinical practice.
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Analysis of Kinetic Programs in the Pure Jatomi Fitness Center Harfa
Nechvílová, Denisa ; Bunc, Václav (advisor) ; Čáslavová, Eva (referee)
Title ANALYSIS OF KINETIC PROGRAMS IN THE PURE JATOMI FITNESS CENTER HARFA Aims The aim of my bachelor thesis is to create a study of offered kinetic programs in the fitness center Pure Jatomi Fitness Harfa. Also I have focused in my work on the person of the coach/instructor of group lessons. Methods I have intentionally chosen fitness center Pure Jatomi Fitness Harfa as the main branch of most developing chain of fitness centers in the Czech republic. The study of kinetic programs itself was made on the basis of research of information from literature and methodical materials for education of instructors. Also in the thesis was used the method of direct observation in above mentioned fitness center and the participation in the lessons of offered kinetic programs as well. An in-depth interviews with employees of the fitness center were carried out, specifically with general manager, fitness manager and also with coaches and instructors of group lessons. During the comparison of competitors was used the method of comparison. Using the SWOT analysis I was trying to find out, what is the real position of the fitness center on the market. Results The results demonstrate information about the kinetic programs of the Pure Jatomi Fitness Harfa company. The mentioned fitness center is compared with...
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