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National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Influence of high level of stress on the adaptative mechanisms of the bones
 Suková, Jaroslava ; Sládek, Vladimír (advisor) ; Struška, Michal (referee)
The main purpose of this paper is to describe the mechanism of the effect of high load on bone tissue and its ability to adapt to the given load. In the first part of this paper I am going to focus on the description of the mechanism of the load effect on bone tissue according to the mechanostat theory of Harold Frost and Jullius Wolff. In the second part I am going to describe how high load affects the bone tissue and how the adaptation mechanisms of the bone will react to the load. In this part I am also going to focus on pathological high load and the occurrence of cracks and fractures on bones due to this load being higher than the bone can sustain. In the last part of the paper I am going to focus on the bone repair mechanisms needed when fractures and cracks disrupt the integrity of the bone. Keywords Adaptability of the bone, physiological mechanisms of the bone, pathological overload, Frost's mechanostat, reparational mechanisms of the bone, bone damage
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