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Simulation of pharmacokinetic models
Hejč, Jakub ; Jiřík, Radovan (referee) ; Mézl, Martin (advisor)
The theoretical part of this project is occupied with analysis of pharmacokinetic actions and also basic attributes of mathematical models used in pharmacokinetics. This description is mainly focused on models used for perfusion imaging methods. The aim of this project is to create an algorithm that simulates chosen models based on assigned parameters and also an algorithm that serves to fit experimentally measured data with a chosen model with a calculation of basic pharmacokinetic parameters. The next step of this solution is graphic interface realization which enables a full use of created algorithm in more accessible surroundings for the user. The result of this work is a program that can be used to obtain real data parameters and as well as a visual sample of the influence of these parameters on a process in a chosen functions.
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The GPU-Based Acceleration of the Genetic Algorithm
Pospíchal, Petr ; Šimek, Václav (referee) ; Jaroš, Jiří (advisor)
This thesis represents master's thesis focused on acceleration of Genetic algorithms using GPU. First chapter deeply analyses Genetic algorithms and corresponding topics like population, chromosome, crossover, mutation and selection. Next part of the thesis shows GPU abilities for unified computing using both DirectX/OpenGL with Cg and specialized GPGPU libraries like CUDA. The fourth chapter focuses on design of GPU implementation using CUDA, coarse-grained and fine-grained GAs are discussed, and completed by sorting and random number generation task accelerated by GPU. Next chapter covers implementation details -- migration, crossover and selection schemes mapped on CUDA software model. All GA elements and quality of GPU results are described in the last chapter.
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Phantom model for perfusion imaging
Borovičková, Michaela ; Harabiš, Vratislav (referee) ; Mézl, Martin (advisor)
This work focuses on issues relating to the perfusion analysis. The aim of this work is to perform experimental measurements of the phantom and then evaluate the perfusion curves. This curves are used to himation of perfusion hemodynamic parameters, which indicates important informatik about monitoring area. All processes associated with the designation and evaluation are performed in a program named Matlab. The output of work is a system that provides the reader into the problem of perfusion analysis and allows him to understand and know what is the meaning od analysis, what demands are placed on the evaluation and what is the result of this perfusion analysis.
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The GPU-Based Acceleration of the Genetic Algorithm
Pospíchal, Petr ; Šimek, Václav (referee) ; Jaroš, Jiří (advisor)
This thesis represents master's thesis focused on acceleration of Genetic algorithms using GPU. First chapter deeply analyses Genetic algorithms and corresponding topics like population, chromosome, crossover, mutation and selection. Next part of the thesis shows GPU abilities for unified computing using both DirectX/OpenGL with Cg and specialized GPGPU libraries like CUDA. The fourth chapter focuses on design of GPU implementation using CUDA, coarse-grained and fine-grained GAs are discussed, and completed by sorting and random number generation task accelerated by GPU. Next chapter covers implementation details -- migration, crossover and selection schemes mapped on CUDA software model. All GA elements and quality of GPU results are described in the last chapter.
|
|
|
Simulation of pharmacokinetic models
Hejč, Jakub ; Jiřík, Radovan (referee) ; Mézl, Martin (advisor)
The theoretical part of this project is occupied with analysis of pharmacokinetic actions and also basic attributes of mathematical models used in pharmacokinetics. This description is mainly focused on models used for perfusion imaging methods. The aim of this project is to create an algorithm that simulates chosen models based on assigned parameters and also an algorithm that serves to fit experimentally measured data with a chosen model with a calculation of basic pharmacokinetic parameters. The next step of this solution is graphic interface realization which enables a full use of created algorithm in more accessible surroundings for the user. The result of this work is a program that can be used to obtain real data parameters and as well as a visual sample of the influence of these parameters on a process in a chosen functions.
|
|
|
Phantom model for perfusion imaging
Borovičková, Michaela ; Harabiš, Vratislav (referee) ; Mézl, Martin (advisor)
This work focuses on issues relating to the perfusion analysis. The aim of this work is to perform experimental measurements of the phantom and then evaluate the perfusion curves. This curves are used to himation of perfusion hemodynamic parameters, which indicates important informatik about monitoring area. All processes associated with the designation and evaluation are performed in a program named Matlab. The output of work is a system that provides the reader into the problem of perfusion analysis and allows him to understand and know what is the meaning od analysis, what demands are placed on the evaluation and what is the result of this perfusion analysis.
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