National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
Activation of human RNase L by 5’-C-phosphonate-modified oligoadenylates
Petrová, Magdalena ; Buděšínský, Miloš ; Zborníková, Eva ; Panova, Natalya ; Novák, Pavel ; Rosenberg, Ivan
Adeno’sine 5’-(S)-C-phosphonate (pCOHX) was prepared as monomer suitable for oligonucleotide synthesis. Modified tetramers pCOHXAAA and pCOHXAApCOHX were assembled on solid phase and evaluated for their ability to activate human RNase L.
Monomery pro nové fosfonátové oligonukleotidy, potenciální inhibitory RNasy L
Liboska, Radek ; Páv, Ondřej ; Rosenberg, Ivan
Synthetic route for the preparation of 2',3'-O-phosphonoalkylidene , and 3',5'-O-phosphonoalkylidene ribonucleotide monomers for automated oligonucleotide synthesis (a phosphotriester condensation approach) has been developed.
Izopolární, izosterní 4'-substituované 2',5'-oligoadenyláty jako potenciální aktivátory RNasy L
Pačes, Ondřej ; Rosenberg, Ivan
Synthesis of two different monomers usable for solid phase synthesis of two basic types of phosphonate and phosphodiester 2’,5’-oligoadenylates as potential activators of RNase L is reported.

Interested in being notified about new results for this query?
Subscribe to the RSS feed.