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Investigation of markers for the diagnostics of metabolic syndrome
KUNEŠ, Jan
In my Bachelor´s thesis I dealt with the issue of investigation of biochemical markers, which are used for diagnostics of metabolic syndrome along with measurement of waist circumference and level of blood pressure. In the theoretical part I defined the term metabolic syndrome. Chapters about glucose and blood lipids tests as well as methods used for their determination are described in detail. Great attention was also paid to preanalytical factors, which significantly share of the accuracy of laboratory test. Practical part of the Bachelor´s thesis is focused on acquisition of practical skills in work with biological material in the laboratory of clinical biochemistry and acquisition of principals of laboratory methods. Under professional supervision in the biochemical laboratory Laboma s.r.o. in České Budějovice, I tested 100 samples of venous blood, where I determined concentration of fasting glucose, triglycerides and HDL cholesterol. The measurement was carried out on the biochemical analyzer Cobas Integra 800 by the method of absorption spectrophotometry. Measured laboratory values were statistically processed and they were interpreted after consultation with the supervisor of the Bachelor´s thesis. The laboratory tests showed that the criteria of metabolic syndrome applied for 21% of women and 15% of men.
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The obesity as an actual problem of today´s society
FRYŠOVÁ, Iveta
This Bachelor Study is on the topic of The obesity as an actual problem of today´s society. Its aim is to summarize the basic topics and questions about the obesity and to show what is the ideal of the body beauty and the body weigh from the view of people who suffer from the obesity, overweight people and also of people with the normal weight. For the research three hypothesis have been set: 1. People suffering from the obesity don´t differ in the point of view of mental representation of the ideal body figure from the common population. 2. The lifestyle of people suffering from the obesity has nothing to do with their conception of the ideal body figure. 3. People suffering from the obesity don´t differ in the point of view of the satisfaction with their body from overweight people. There have been chosen a quantitative {--} qualitative research. The questionnaire was wholly anonymous. The research took place in January and February 2007. First hypothesis was refuted. Second and third hypothesis were confirmed. In my opinion the aim of the Study was accomplished. There are many of TV programmes, books, magazines or web sites that attent to the obesity. The reason is that the number of people who suffer from this disease grows up in whole Europe. The obesity is defined as an excessive physical mass with increased portion of the adipose tissue. It is not only the aesthetic problem. The obesity can cause many health problems, e.g. diabetes mellitus, hypertension, cancer, gynaecologist problems, cardiac or joint diseases. This condition can also have an impact on the human mental sphere and depressions or anxiety can occur. Today ´s ideal of the body beauty is a very thin figure. Women and girls are forced to be on a diet. There are more and more people who just only think that they are overweight or obese. The diet industry has gigantic power to support the idealization of the slimness.
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PROBLEMS OF DIAGNOSTIC IMAGING IN THE OBEZITY AND METABOLIC SYNDROM
VLKOVÁ, Renata
Metabolic syndrome is characterised by a combination of metabolic disorders and diseases with very serious consequences. Obesity is defined as being overweight with a high proportion of fatty tissue. According to the WHO, obesity is considered a serious epidemic of the 21st century. The aim of this work is to summarise mentioned issues from the available literature and to describe individual imaging modalities in diagnostic radiology related to metabolic syndrome, together with the evaluation of fat tissue distribution in the abdominal area, including its changes, after nutritional education and treatment in a monitored patient group. Participants have been randomised for the study group from the Centre for Adult Obesity and their BMI had to exceed 25. The main requirements were a voluntary cooperation, non-pharmacological methods of obesity treatment and weight limited to 140 kg. All of the addressed patients have shown their interest and willingness to continue this cooperation in the future.
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The Imaging in Cases of Obesity and the Metabolic Syndrome
DUŠKOVÁ, Radka
This thesis deals with imaging in cases of obesity and the metabolic syndrome. It mainly focuses on the diagnostic imaging using imaging modalities, such as skiagraphy,skiascopy, ultrasonography, computer telegraphy and magnetic resonance. The objective of this thesis was to determine the characteristic and specific qualities of various diagnostic procedures of a radiological assistant when imaging patients suffering from obesity and the metabolic syndrome, especially when a contrast medium is used during the treatment, and then to compare the diagnostic possibilities of imaging when different imaging modalities are used. The theoretical part describes obesity and the metabolic syndrome, with the special focus being done on their possible extent and resulting complications. Theimaging modalities do not image obesity and the metabolic syndrome as such, but deal with the diagnostics and the treatment of various illnesses caused by metabolic dysfunctions. The issue of diagnostic imaging is complicated by the differences in methods caused by the use or non-use of ionizing radiation. The increased risk of complications during the treatment of patients suffering from obesity and the metabolic syndrome can be caused by the use of a contrast medium, which is mostly used in diagnostic imaging and it is also sometimes used in therapeutic imaging, such the invasive treatment of the cardiovascular system. For this reason, this issue has also been dealt with in this thesis. The practical part contains an evaluation and a comparison of 100 questionnaires that have been filled in by randomly selected patients of the Radiological Department.The questionnaires were anonymous and those questions were created so as to determine the prevalence of obesity in the investigated sample, which would then provide information about the possible complications that can occur during an examination which have been caused by obesity and the metabolic syndrome. After completion of the questionnaire by these patients, I also participated in their examination and verified my presupposed hypothesis in practice. The results of the questionnaire research and the participation in the examination of respondents confirmed my hypothesis that imaging in obesity and the metabolic syndrome requires a special approach, especially when contrast mediums are used during the treatment. Attention has to be paid not only to the technical modifications of procedures in individual imaging modalities, but also to the specifications connected with organ polymorbidity and the related complicating pathological conditions. Since the prevalence of obesity and the metabolic syndrome is increasing, it is very probable that we will meet patients suffering from this type of illness increasingly more often at the Radiological Department. This is another reason why the specificities of imaging patients suffering from these illnesses should be gradually implemented into regular radiological imaging procedures.
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