|
|
Verification of the authenticity of remains of 18th century medicinal products containing juniper or liquorice
Lener, Tomáš ; Nesměrák, Karel (advisor) ; Kubíčková, Anna (referee)
Three remains of historical pharmaceuticals from 18th century containing juniper (Rob juniperi, Lignum juniperi) or liquorice (Pulvis radicis liquiritiae) were analyzed by HPLC-MS method and their authenticity was verified using a chemotaxonomic approach. Current reference material was the source of chemotaxonomic markers and also a raw material for replication of Rob juniperi according to two period recepies. HPLC-MS method provided good results but wasinsufficienttoanalyzeLignumjuniperi.Therefore,GC-MSmethod wasalsousedto analyzethejunipersamplesand it provided sufficient results to prove the authenticity of both juniper samples. HPLC-MS method identified viridiflorin heptoside for the first time in juniper material, for which as well as for five liquorice markers ESI fragmentation spectra weremeasured and theirpossiblefragmentation mechanismwasproposed.Based on theobtained results, thepreparation ofhistorical samplesfrom the mentioned plants can beconfirmed. Key words: HPLC-MS, GC-MS,Chemotaxonomy, Juniper,Liquorice, Tandemmass spectrometry,Viridiflorin
|
|
| |
|
|
Zhodnocení rodu Juniperus L. z pohledu použití v ZKT
Adel, Aleš
Juniperus L. is one of the most diverse genera of the conifers, thus having a wide variety of use in garden and landscape work. This bachelor's thesis deals with studying the genus and its species primarily from the perspective of systematics and terminology, chorology, botanical description and introduction on the region of Europe and the Czech Republic. Furthemore it concerns the compositional, ecological and growing characteristics that affect the use of each of the taxons in garden and landscape design. The work also includes evaluation of the current offer of nursery products and more detailed description of selected representatives.
|
|
| |
|
| |
guest ::
