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Effect of electrical stimulation on soft tissue healing
Fošumpaur, Karel ; Jeníček, Jakub (advisor) ; Angerová, Yvona (referee)
First and last name: Karel Fošumpaur Supervisor: Mgr. Jakub Jeníček, Ph.D. Opponent of the thesis: Name of the thesis: Effect of electrical stimulation on soft tissue healing Abstract of the thesis: This bachelor thesis summarizes the current state of knowledge regarding the effectiveness of electrical stimulation on soft tissue healing by providing an overview of the issue. The aim of the thesis is to describe the current level of research on the subject in terms of its completeness, current stage and limitations. Fifteen peer-reviewed, relevant articles were included and analyzed through a systematic search. Through analytical analysis and evaluation of the studies, it is determined whether and under what conditions electrical stimulation is effective for soft tissue healing. The articles presented include studies testing the effectiveness of electrical stimulation for healing structurally damaged muscle, tendon, skin and ligament. The work provides a largely positive conclusion regarding the healing effect of electrical stimulation. Key words: electrical stimulation, healing, soft tissue, muscle, tendon, skin, connective tissue, ligament, regeneration, reparation, electrotherapy
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Regeneration of heart muscle in vertebrates
Bergelová, Barbora ; Krylov, Vladimír (advisor) ; Mašek, Jan (referee)
Fish model organisms such a Danio rerio have the ability to regenerate heart muscle during its whole lifespan. Compared to Danio rerio, the ability of heart regeneration differs in amphibians. While the newt has the ability to regenerate its heart tissue throughout its whole life, the Xenopus leavis loses its power when it goes through metamorphosis. The regenerative ability varies not only between genera but also between species. For example compared to Xenopus leavis, Xenopus tropicalis has the ability to regenerate its heart tissue even in adulthood. Mammals have a very limited ability to regenerate their heart muscle. We can observe the ability to regenerate heart after injury in mice and humans for a very limited time of a few days after birth. In adulhood the heart is healed via rich collagen scar. It is vital that signaling pathways in highly regenerative model organisms are intensively studied, so that the knowledge gained may help us in the treatment of heart injuries in humans. Key words: regeneration, heart muscle, repair, zebrafish, mammals, amphibians, heart development, vertebrates
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Regeneration of heart muscle in vertebrates
Bergelová, Barbora ; Krylov, Vladimír (advisor) ; Mašek, Jan (referee)
The model organisms like for example the fish Danio rerio has the ability to regenerate heart muscle during its whole lifespan. Compared to Danio rerio, the ability of heart regeneration differs in amphibians. While the newt has the ability to regenerate its heart tissue throughout its whole life, the Xenopus leavis loses its power when it goes through metamorphosis. The regenerative ability does not only differ between salamanders and claws. We can observe some differences between regeneration of Xenopus tropicalis and Xenopus leavis too. Compared to Xenopus leavis, Xenopus tropicalis has the ability to regenerate its heart tissue even in adulthood. Mammals have a very limited ability to regenerate their heart muscle. We can observe the ability to reverse heart damage in mice and humans for a very limited time of a few days after they are born. In adulhood they repair the heart muscle and the rich collagen scar is formed. It is vital that signaling pathways in regeneration of model organisms is researched further, so that the knowledge gained may help us in the treatment of heart injuries in humans. Key words: regeneration, heart muscle, repair, zebrafish, mammals, amphibians, heart development, vertebrates
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The role of nitric oxide during embryonic wound healing and regeneration
Abaffy, Pavel ; Šindelka, Radek (advisor) ; Brábek, Jan (referee) ; Krylov, Vladimír (referee)
The study of the mechanisms that control wound healing is an attention-drawing area within the fields of biology and medicine. Wound healing can be usually defined as two basic types. The first type is adult wound healing, which is slow and results in the scar formation. The second type is referred to as embryonic wound healing, which is in contrast fast and scarless. Wound healing is a complicated process that includes many steps, which are regulated by various types of molecules. One of these important molecules is nitric oxide (NO). Its function is usually connected with the regulation of inflammation and angiogenesis during adult wound healing. However, there is currently no information on its role during embryonic wound healing, where the immune and vascular systems are not yet developed. In this work, we explore and describe the role of the NO during the healing of the early embryos. The highest concentration of the NO post wounding is produced during the first 30 minutes after injury. This applies to all developmental stages, from the blastula stage all the way to the swimming tadpole stage. The main role of the NO during embryonic wound healing is the regulation of the gene expression that is connected with the stress response and the regulation of cellular metabolism. Additionally, we...
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Case study of physiotherapy treatment of a patient with the diagnosis
Jorlo, Johanne Marie ; Maršáková, Kateřina (advisor) ; Zemlerová, Hana (referee)
Title: Case study of physiotherapy treatment of a patient following total knee replacement Abstract: The aim of the thesis is to present the physiotherapy given to a patient with stiffness after an atypical total knee replacement procedure. The work consists of a general part and a special part. The general part aims to explain this particular case of total knee replacement from a theoretical point of view. The goal of the special part is to present physiotherapy as treatment, it's conduction and results. Method: One female patient (b. 1958) with chronic stiffness following total knee replacement was selected and gave consent to take part in the case study. A copy of the form of consent can be found in the appendix at the end of this thesis. Clinical examination, therapy and progress evaluation took place at Rehabilitation Clinic Malvazinky from 21.01.14 to 31.01.14 under the supervision of Mgr. Hana Zemlerová. Utilities used in examination and treatment included treatment table, measuring tape, neurologic hammer, goniometer, overball, big balls, bosu balls, spiked balls, supportive pillows, stationary bicycle and mats. Therapeutic methods and principles used was PIR, soft tissue techniques, joint manipulation and posture correction. The general part was based on theory learned through the bachelor...
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The usage of modern methods of moist healing in practice
TETALOVÁ, Veronika
ABSTRACT The usage of modern methods of moist healing in practice Introduction: The method of moist healing has been reintroduced in practice during the last years. This revolutionary change does not only concern the usage of specific materials and a complex approach to solving the problem, but also doctors, medical staff and even patients have started to be more interested in this specific topic. The development of modern way how to heal wounds in practice has divided medical staff into two groups; the ones who specialize in this method and the ones who respect new possibilities, however, have little experience with the issue. Objective: The aim of my bachelor thesis is to find out whether nurses make a choice in kinds of material used for moist wound healing according to the phase of wound healing (TIME system), if the materials are used more preventively or therapeutically and finally, whether nurses cooperate with doctors on the choice of material. The research sample was formed by 89 nurses working in standard departments (e.g. department of surgery, department of internal medicine, department of subsequent care) in Hospital Ceske Budejovice, JSC and Hospital Prachatice JSC. Results: I have discovered that my hypothesis (H3) ? nurses cooperate with doctors on the choice of material used for moist healing is confirmed. Hypothesis (H2) said that the materials used for moist healing are used mostly therapeutically in practice. According to the survey, I have discovered that nowadays these materials are mostly used either therapeutically or preventively. The result is presented in graph 15. As it was found out, materials used for moist wound healing are used in 57 % therapeutically as well as preventively in hospital care and only in 43% therapeutically. Hypothesis H2 is not confirmed. My hypothesis (H1) said: ?The choice of material used for moist healing is performed according to the phase of wound healing?. The results surprised me hence the hypothesis is not confirmed. Only 48 % of the respondents use TIME system. The difference between the usage and no usage of TIME system is only 4 %, which amounts to 3 people out of the total number of 75 respondents (100 %). Conclusion: The results of my research could be used for an extended research, as a source for standards and seminars for nurses and also for an article published in a specialized magazine.
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Using services of the Centres of wet healing of wounds by primary care nurses
POLNICKÁ, Ludmila
Treatment of chronic wounds is a complicated multidisciplinary problem. Modern therapeutic dressings which are permeable and keep the wound wet play an important role in the treatment. At present many professionals strive for support and wider spread of wet wound healing in the Czech Republic. They are mostly nurse organisations, journals, pharmaceutical firms and ``Centres of wet wound healing``. The Centre of Vysočina region is in Jihlava. Centre staff help nurses, doctors and patients to improve the care of wounds. As seen from the results, in spite of all obstacles which nurses have to face while using modern therapeutical dressings the method of wet wound healing in the treatment is spreading. More and more nurses use this method. The Centre of wet wound healing and departments for chronic wounds help towards this effort.
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Primary care nurses experience with wound treatment
ČEJKOVÁ, Jana
In this work study ``Experiences of nurses of primary care with wounds healing{\crqq} there are two main relevant questions {--} primary care of patients and wounds healing. Process of wounds healing has been for many years in significant attention of some medical branches. According to this interest many useful studies, discoveries and researches have been done. Wounds healing is not according to only affected locality, but also to the whole organism, immune system, metabolism, nourishment and many other aspects referential to this question. Patients with wounds can have more comfortable health care due to interests for tissue defects. However lots of experts try to implement new methods of wounds healing, majority of clients meet still the out of date therapies. Some kinds of primary health care have been used for a long time, other ones used to be used a long time ago and now are again renovating. All providers of primary health care are under capacity, financial and legislative pressure and so are not able to provide this health care in full extent. The aim of this study was to find ``Experiences of nurses of primary care with different materials for wounds healing{\crqq}. For this aim the hypothesis ``Nurses of primary care have not enough experiences with modern methods of wounds healing{\crqq} was settled. The second aim was ``To discover the interests of nurses of primary care for new experiences of wounds healing{\crqq}. This aim was encouraged by hypothesis ``Nurses have interests about new experiences of wounds healing{\crqq}. The information needed for this research were taken by questionnaires given to nurses working by general practitioners in České Budějovice and Benešov. Answers of 50 nurses were used for data processing. The hypothesis that nurses do not have enough experiences with wounds healing was confirmed. The second hypothesis was also confirmed. My work study could be useful for nurses of primary health care as summary of actual situation and so could improve the health care for clients.
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