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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Analýza, separace a studium vztahu mezi strukturou a pohyblivostí biopeptidů kapilární zónovou elektroforézou
 Šolínová, Veronika ; Kašička, Václav ; Koval, Dušan ; Hlaváček, Jan ; Barth, Tomislav
Capillary zone electrophoresis has been applied to the analysis, separation and physicochemical characterization of synthetic biopeptides such as insect oostatic peptides, enkephalins and dalargin.
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Receptor-selective enkephalin analogs
 Pencheva, N. ; Barth, Tomislav
We investigated the opioid profiles of [Cys2]-enkephalin (enk) analogs and [D-Ala2,Leu5]-enkephalyl-Arg (dalargin) in in vitro bioassay system. The results showed that incorporation of hydrophilic Cys(O2NH2)2 into the enk molecule greatly increases the potency and selectivity of the analogs to ë-opioid receptors, while substitution of D-Ala2 and Arg6 into the molecule of [Leu5]-enk, to ć-opioid receptors.
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