National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Defence of organism against reactive oxide substances and the role of nutrition in it
BENDLOVÁ, Radka
Reactive oxygen and nitrogen species along with environmental toxins are the most frequently cited sources of pathological effects on physiological proceses in man and on the development of degenerative diseases (diseases of civilization). Numerous free radicals commonly occur in the organism because they are part of physiological processes (physical exercive, food processing, the body's immune defence). On one hand highly reactive oxygen species play an important role in antimicrobial protection of the human body, helping to kill microorganismus during phagocytosis. Other side of oxidative stress (overproduction of reactive oxygenates) participates damage to proteins, lipids and nucleic acids. Oxidative damage to biomolecules has to be counteracted by antioxidant defense. Sufficient level of antioxidants in biological tissues act protectively. If we follow the recommended quantity and composition of food rich in antioxidants we can substantially contribute to improving our health and reduce the risk of manifestation of the serious diseases, so called civilization diseases.
Factors influencing changes to the content of antioxidants in the body.
MERLEOVÁ, Gabriela
This thesis deals with the relationship between antioxidants and free radicals, their interactions and effects on the human body. Characteristics, properties and occurrence of some antioxidants such as carotenoids, flavonoids, ascorbic acid, selenium, melatonin, quercetin, etc., may explain some of the mechanisms of their effects on human health, particularly in the area of lifestyle diseases such as cardiovascular disease, cancer and obesity. Fruits and vegetables are important sources of dietary antioxidants and therefore are regularly added to the diet part of the antioxidant defense of the organism, although the content of antioxidants in these foods may be changed by external influences. Information used in this study were obtained from the scientific and professional publications and periodicals found in domestic and international databases of scientific and specialist literature.

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