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The effect of cold exposure on regeneration in skeletal muscle
Novotná, Veronika ; Kašík, Petr (advisor) ; Vašek, Daniel (referee)
Cold is a stressful stimulus to which the body responds with an extensive physiological response, making it important to understand its complex effects. Skeletal muscle is an important thermoregulatory organ and helps maintain a constant body temperature by both shivering and non-shivering thermogenesis. At the same time, it has a considerable regenerative capacity that is modulated by the inflammatory immune response. This paper summarizes the effects of cold on skeletal muscle regeneration and the inflammatory response that is triggered after intense exercise or skeletal muscle injury. The inflammatory response is essential for the successful completion of skeletal muscle regeneration, and if it is impaired, it can have a negative effect on muscle tissue recovery. The balance between the pro-inflammatory and anti-inflammatory phases of the immune response, which is determined by the presence of specific immune cell populations and cytokine release, is crucial. Cold exposure is generally accepted as an effective strategy to improve skeletal muscle regeneration, but the molecular basis of this effect is not fully understood, and thus the observation of the effect of cold on skeletal muscle regeneration is still a actual topic. Keywords: cold exposure, inflammation, skeletal muscle, regeneration,...
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An effect of cold showers on physical characteristics of adults
ANDERLOVÁ, Štěpánka
The bachelor thesis is focused on the behavior of brown adipose tissue (BAT) when activated by cold exposure. Non-shaking thermogenesis then takes place in this tissue, during which heat is generated. For this reason, it is possible to activate BAT with a cold shower, during which a given thermogenesis takes place, and to monitor the impact on the change in the physical charakteristics of an adult. The cold showers research involved 48 students aged 19-26 who took a shower with cold water several times a week. One group was taking cold showers for 11 months, the other for three months. Their body composition was measured with a Bodystat device and skin folds was measured at four parts of the body using a caliper, always at the beginning and at the end of the research. The measured data were processed and evaluated. An important result can be found in experimental groups, where with increasing number of cold showers there was an increase in adipose tissue, even though the result is not statistically significant.
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